Z. Zou

Publications20
h-index11
Citations397
Highly Influential Citations29
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Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis
Background Genetic studies have shown that C9orf72, SOD1, TARDBP and FUS are the most common mutated genes in amyotrophic lateral sclerosis (ALS). Here, we performed a meta-analysis to determine the… Expand
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De novo FUS gene mutations are associated with juvenile-onset sporadic amyotrophic lateral sclerosis in China
Juvenile amyotrophic lateral sclerosis (ALS) is a rare form of motor neuron disease and occurs before 25 years of age. Only very few sporadic cases of juvenile-onset ALS have been reported. Rare SOD1… Expand
  • 56
  • 4
Screening for C9orf72 repeat expansions in Chinese amyotrophic lateral sclerosis patients
An intronic GGGGCC hexanucleotide repeat expansion in the C9orf72 gene was recently identified as a major cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia in white… Expand
  • 51
  • 2
Identification of a novel missense mutation in angiogenin in a Chinese amyotrophic lateral sclerosis cohort
Abstract Angiogenin (ANG) gene mutations have been identified in both familial and sporadic amyotrophic lateral sclerosis (ALS) patients from multiple European and North American populations.… Expand
  • 18
  • 2
Toward precision medicine in amyotrophic lateral sclerosis.
Precision medicine is an innovative approach that uses emerging biomedical technologies to deliver optimally targeted and timed interventions, customized to the molecular drivers of an individual's… Expand
  • 13
  • 2
Short-term versus long-term hormone therapy plus radiotherapy or prostatectomy for prostate cancer: a systematic review and meta-analysis
PurposeTo compare the efficacy and safety of short-term versus long-term hormonotherapy (HT) plus radiotherapy (RT) or prostatectomy (RP) for prostate cancer.MethodsLiteratures were searched from… Expand
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  • 2
Screening of VCP mutations in Chinese amyotrophic lateral sclerosis patients
Mutations in valosin-containing protein (VCP) gene have been recently found in familial and sporadic amyotrophic lateral sclerosis (ALS). To define the frequency of VCP mutations in ALS patients in… Expand
  • 28
  • 1
Screening of the TARDBP gene in familial and sporadic amyotrophic lateral sclerosis patients of Chinese origin
TAR DNA-binding protein (TARDBP) mutations have been reported in patients with amyotrophic lateral sclerosis (ALS) in different populations. Only a few studies have screened for TARDBP mutations in… Expand
  • 23
  • 1
Abnormal cerebral microstructures revealed by diffusion kurtosis imaging in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease in which cerebral structural impairment is a consistent feature.
  • 3
  • 1
Mutations in the profilin 1 gene are not common in amyotrophic lateral sclerosis of Chinese origin
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease primarily involving the corticospinal tract, brainstem, and anterior cells of the spinal cord. Mutations in the profilin… Expand
  • 17