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Buspirone
Known as:
Buspiron
, N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-1-cyclopentanediacetamide
, Buspirone [Chemical/Ingredient]
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An anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact…
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National Institutes of Health
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Related topics
Related topics
32 relations
Narrower (11)
1-(2-pyridinyl)piperazine
1-(2-pyrimidinyl)piperazine
6-hydroxybuspirone
Anxut
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Broader (6)
Anti-Anxiety Agents
Hypnotics and Sedatives
Pyrimidines
Serotonin Agonists
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Anxiety Disorders
Buspirone:MCnc:Pt:Ser/Plas:Qn
CYP3A7 protein, human
Depressive disorder
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
CYTOCHROME P 450 3 A-MEDIATED METABOLISM OF BUSPIRONE IN HUMAN LIVER MICROSOMES
Mingshe Zhu
,
Weiping Zhao
,
+5 authors
J. Mitroka
2005
Corpus ID: 37465473
This study was carried out to determine the metabolic pathways of buspirone and cytochrome P450 (P450) isoform(s) responsible for…
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2004
2004
Pharmacologic Treatment of Equine Self-Mutilation Syndrome
N. Dodman
,
L. Shuster
,
G. Patronek
,
L. Kinney
2004
Corpus ID: 10105257
The effects of drugs that either stimulate or inhibit central opioid, dopamine, norepinephrine, and serotonin neurotransmitter…
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1994
1994
Buspirone:seven-year update.
Journal of Clinical Psychiatry
1994
Corpus ID: 13396377
1993
1993
Buspirone in progressive myoclonus epilepsy.
M. Pranzatelli
,
D. Franz
,
E. Tate
,
J. M. Martens
Journal of Neurology Neurosurgery & Psychiatry
1993
Corpus ID: 19292505
conduction studies revealed no abnormalities in the face, upper or lower extremities. Supramaximal stimulation of the tibial…
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1989
1989
Buspirone, gepirone and ipsapirone disrupt both active and passive avoidance responding in rats
D. Sanger
,
D. Joly
,
M. LePichon
Behavioural Pharmacology
1989
Corpus ID: 37388739
The anxiolytic drug buspirone and its structural analogues gepirone and ipsapirone produce behavioural effects which differ from…
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Review
1989
Review
1989
The clinical utility of pharmacological agents that act at serotonin receptors.
S. Peroutka
,
A. Sleight
,
B. G. McCarthy
,
P. Pierce
,
Anne W. Schmidt
,
C. R. Hekmatpanah
The Journal of Neuropsychiatry and Clinical…
1989
Corpus ID: 31757261
The past decade has seen important advances in the clinical utility of serotonergic agents. The putative novel anxiolytic effects…
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1987
1987
Serum prolactin levels after buspirone in man.
T. Seppälä
,
T. Ranta
,
R. Shrotriya
Medical biology
1987
Corpus ID: 37437403
The acute effects of buspirone, an anxiolytic with mixed dopamine (DA) agonist-antagonist properties (achieved by blocking pre…
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Highly Cited
1986
Highly Cited
1986
Effects of buspirone and diazepam, alone and in combination with alcohol, on skilled performance and evoked potentials.
C. Erwin
,
M. Linnoila
,
J. Hartwell
,
A. Erwin
,
Sally Guthrie
Journal of Clinical Psychopharmacology
1986
Corpus ID: 26164827
Effects of buspirone, 10 and 20 mg, and diazepam, 10 mg, on skilled performance and evoked responses, as well as their…
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1986
1986
Buspirone analogues. 2. Structure-activity relationships of aromatic imide derivatives.
J. New
,
J. Yevich
,
+5 authors
D. Temple
Journal of Medicinal Chemistry
1986
Corpus ID: 31083788
Several analogues of the novel anxiolytic buspirone were synthesized and evaluated in vivo for tranquilizing activity and their…
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Review
1986
Review
1986
Anxiolytics and the alcoholic patient.
R. Meyer
Journal of Studies on Alcohol
1986
Corpus ID: 41018964
There is a growing appreciation of the heterogeneity of alcoholic patients with implications for treatment intervention. Several…
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