Buspirone

Known as: Buspiron, N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-1-cyclopentanediacetamide, Buspirone [Chemical/Ingredient] 
An anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Zebrafish are becoming more widely used to study neurobehavioral pharmacology. We have developed a method to assess novel… (More)
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Highly Cited
2007
Highly Cited
2007
Dopamine (DA) replacement therapy with l-DOPA remains the standard pharmacotherapy for Parkinson's disease (PD). Unfortunately… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Although clinicians frequently add a second medication to an initial, ineffective antidepressant drug, no randomized… (More)
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Highly Cited
2004
Highly Cited
2004
STAR*D is a multisite, prospective, randomized, multistep clinical trial of outpatients with nonpsychotic major depressive… (More)
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Highly Cited
2001
Highly Cited
2001
UNLABELLED Mild hypothermia (i.e., 34 degrees C) may prove therapeutic for patients with stroke, but it usually provokes… (More)
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Highly Cited
1994
Highly Cited
1994
We made a double-blind, crossover comparison of buspirone (10 mg orally, twice a day) and placebo in 10 patients with Parkinson's… (More)
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Highly Cited
1986
Highly Cited
1986
The current studies further investigated the effects, in animal models of anxiety, of novel putative anxiolytic and anxiogenic… (More)
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Review
1986
Review
1986
The metabolism and disposition of buspirone have been studied in the rat, the monkey, and in more than 150 human subjects… (More)
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1982
1982
Biochemically, buspirone is unlike the benzodiazepines in that it neither stimulates nor inhibits 3H-benzodiazepine binding, does… (More)
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Highly Cited
1982
Highly Cited
1982
The anxiolytic properties of buspirone were assessed in a 4-week double-blind study in 240 anxious patients, 81 of whom received… (More)
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