Budesonide Enema

Background  Rectal budesonide is an effective treatment of active ulcerative proctitis or proctosigmoiditis. 

Pouchitis has been suggested to be a recurrence of ulcerative colitis in a colon‐like mucosa. Topical steroids are a valid… Expand

Background: Glucocorticosteroid enemas are equally effective as 5-ASA enemas in the treatment of active distal ulcerative colitis… Expand

BACKGROUND & AIMS Budesonide is a highly potent topical glucocorticosteroid that is characterized by low systemic availability as… Expand

Background: Budesonide is a new corticosteroid with high topical anti‐inflammatory activity but little systemic effect. The aim… Expand

Methods: Efficacy and safety of the topically acting glucocorticosteroid budesonide retention enema (2.3 mg/ 11 5 mL) were… Expand

Background: The aim was to compare budesonide enema, 2 mg/100 mL (Entocort) and hydrocortisone acetate foam enema, 125 mg… Expand

Pharmacokinetic data obtained after one dose of a 2‐mg budesonide enema were compared with data obtained after the last dose of… Expand

The aim of this study was to evaluate whether budesonide enema (2 mg/100 ml) had a significantly better effect than placebo in… Expand

Sixty-four patients with active distal ulcerative colitis participated in a multicentre, randomized, investigator-blind trial to… Expand