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Brinolase

Known as: Brinase, Brinolase [Chemical/Ingredient] 
A fibrinolytic and thrombolytic enzyme from Aspergillus oryzae. EC 3.4.99.-.
National Institutes of Health

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ASPERGILLUS FLAVUS VAR. ORYZAE PROTEASEIn BloodProcess of secretionantagonists & inhibitors

Broader (1)

Fibrinolytic Agents

Papers overview

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1994
1994
Encapsulation of the thrombolytic enzyme, brinase, in photosensitized erythrocytes: a novel thrombolytic system based on photodynamic activation.
1981
1981
Studies on the Degradation of Fibrinogen by Proteolytic Enzymes from the Larvae of Lanomia achelous (Cramer)
Summary Fibrinogen degradation products formed by the action of purified haemolymph and saliva of a Satumidae caterpillar of the… 
1979
1979
Relief of chronic arterial obstruction using intravenous brinase. A control study.
A therapeutic trial using placebo or the thrombolytic enzyme brinase was carried out in a group of patients with chronic arterial… 
Highly Cited
1975
Highly Cited
1975
Adjuvant therapy of cancer via the cellular immune mechanism or fibrin by induced fibrinolysis and oral anticoagulants
The value of the oral anticoagulant warfarin sodium and fibrinolytic agents is discussed in relation to cancer surgery. A… 
1975
1975
Thrombolytic Treatment With I.V. Brinase of Advanced Arterial Obliterative Disease of the Limbs
The material includes 17 patients suffering from different degrees of chronic peripheral arterial disease (11 chronic patients… 
1974
1974
Unblocking or activation of the cellular immune mechanism by induced proteolysis in patients with cancer.
1974
1974
Degradation of non cross-linked and cross-linked fibrin clots by plasmin, trypsin, chymotrypsin and Brinase.
1972
1972
Thrombolytic treatment with Brinase of dogs with experimental pulmonary embolism.
Thrombolysis by means of Aspergillus oryzae protease was studied in mongrel dogs of both sexes with experimentally induced… 
1972
1972
The use of the proteolytic enzyme brinase to produce autocytotoxicity in patients with acute leukemia and its possible role in immunotherapy.
Summary Daily infusion of brinase (Protease 1 of Aspergillus oryzae ) for 10 to 30 days in six patients (three children, three… 
1971
1971
The effects of protease I of Aspergillus oryzae (brinase) on membrane permeability and growth of landschütz ascites tumour cells
Landschütz ascites tumour cells treated in vitro with Protease I showed no changes in intracellular K and Na levels when the… 
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