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Brain-specific Angiogenesis Inhibitor 1

Known as: BAI1 
Brain-specific angiogenesis inhibitor 1 (1584 aa, ~174 kDa) is encoded by the human BAI1 gene. This protein may play a role in signal transduction… Expand
National Institutes of Health

Related topics

Related topics

6 relations
ADGRB1 geneAngiogenesis Inhibitory ProteinAngiogenic ProcessCell Adhesion
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Papers overview

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Highly Cited
2013
Highly Cited
2013
Brain-specific Angiogenesis Inhibitor-1 Signaling, Regulation, and Enrichment in the Postsynaptic Density*
Background: BAI1 is an adhesion receptor; little is known about its signaling or localization. Results: BAI1 activates Rho in a G… Expand
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Review
2011
Review
2011
Emerging roles for the BAI1 protein family in the regulation of phagocytosis, synaptogenesis, neurovasculature, and tumor development
While G-protein-coupled receptors (GPCRs) have received considerable attention for their biological activity in a diversity of… Expand
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Highly Cited
2011
Highly Cited
2011
Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria
Bacterial recognition by host cells is essential for initiation of infection and the host response. Bacteria interact with host… Expand
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2011
2011
Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1.
Brain angiogenesis inhibitor 1 (BAI1) is a putative G protein-coupled receptor with potent antiangiogenic and antitumorigenic… Expand
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2007
2007
Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
This study was designed to elucidate the therapeutic effect of transfering the brain-specific angiogenesis inhibitor 1 (BAI1… Expand
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Highly Cited
2007
Highly Cited
2007
Gene expression profiling of metastatic brain cancer.
Gene expression profiling of metastatic brain tumors from primary lung adenocarcinoma, using a 17k-expression array, revealed… Expand
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2004
2004
Extracellular fragment of brain-specific angiogenesis inhibitor 1 suppresses endothelial cell proliferation by blocking alphavbeta5 integrin.
Brain-specific angiogenesis inhibitor 1 (BAI1) is a transmembrane protein with anti-angiogenic activity. The mechanisms… Expand
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2002
2002
Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells
Brain-specific angiogenesis inhibitor 1 (BAI1) is a p53-target gene specifically expressed in the brain. We examined the… Expand
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2000
2000
Vascularization is decreased in pulmonary adenocarcinoma expressing brain-specific angiogenesis inhibitor 1 (BAI1).
Brain-specific angiogenesis inhibitor 1 (BAI1) is a novel angioinhibitory factor. We examined BAI1 gene expression in 48… Expand
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1998
1998
Brain-specific angiogenesis inhibitor 1 expression is inversely correlated with vascularity and distant metastasis of colorectal cancer.
Brain-specific angiogenesis inhibitor (BAI) 1 was recently isolated as a novel p53 inducible gene. BAI1 has been suggested to… Expand
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