Blastodisc

Known as: Areas, Germinal, Germinal Area, Germinal Discs 
A small whitish spot on the surface of the EGG YOLK where cleavage begins. Upon fertilization the cytoplasm streams from the vegetal pole away from… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
During immune responses, B lymphocytes clonally expand and undergo secondary diversification of their immunoglobulin genes in… (More)
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Highly Cited
2010
Highly Cited
2010
Germinal centers (GCs) are sites of B cell proliferation, somatic hypermutation, and selection of variants with improved affinity… (More)
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Review
2010
Review
2010
Germinal centers (GCs) are specialized microenvironments formed after infection where activated B cells can mutate their B-cell… (More)
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Highly Cited
2006
Highly Cited
2006
B cells responding to T-dependent antigen either differentiate rapidly into extrafollicular plasma cells or enter germinal… (More)
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Highly Cited
1998
Highly Cited
1998
To examine the role of germinal centers (GCs) in the generation and selection of high affinity antibody-forming cells (AFCs), we… (More)
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Review
1998
Review
1998
In the human, most IgM+IgD+ as well as CD5+ peripheral blood B cells express unmutated V genes and thus can be assigned to a pre… (More)
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Review
1994
Review
1994
Germinal centers develop in the B cell follicles of secondary lymphoid tissues during T cell-dependent (TD) antibody responses… (More)
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Highly Cited
1992
Highly Cited
1992
In the genetically restricted response that follows immunization with (4-hydroxy-3-nitrophenyl)acetyl coupled to protein carriers… (More)
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Highly Cited
1991
Highly Cited
1991
Germinal centers develop in peripheral lymphatic tissue during the primary immune response and may play a crucial role in… (More)
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Highly Cited
1987
Highly Cited
1987
QH1, a monoclonal antibody that recognizes quail endothelial and haemopoietic cells, was applied to quail blastodiscs in toto, in… (More)
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