Biospecimen Core Resource Facility

Known as: BCR, Biospecimen Core Resource 
A central facility to qualify, quality assure, and distribute human biomolecules in support of the development of the Cancer Genome Atlas (TCGA… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Antiapoptotic members of the bcl-2 family have recently been implicated in the pathogenesis of chronic myeloid leukemia (CML), a… (More)
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Review
2004
Review
2004
The prototypic non-receptor tyrosine kinase c-Abl is implicated in various cellular processes. Its oncogenic counterpart, the Bcr… (More)
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Highly Cited
2004
Highly Cited
2004
We previously showed that type I interferon-induced, Cre-mediated ablation of surface BCR expression in mature B cells through Ig… (More)
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Highly Cited
2002
Highly Cited
2002
Through sequencing analysis of blood or bone marrow samples from patients with chronic myeloid leukemia, we identified BCR-ABL… (More)
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Highly Cited
2002
Highly Cited
2002
Clinical resistance to imatinib mesylate is commonly observed in patients with advanced Philadelphia chromosome- positive (Ph… (More)
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Highly Cited
2000
Highly Cited
2000
Cancer is thought to arise from multiple genetic events that establish irreversible malignancy. A different mechanism might be… (More)
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Highly Cited
1999
Highly Cited
1999
Signal transducer and activator of transcription (STAT)5 is constitutively activated in BCR/ ABL-expressing cells, but the… (More)
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Highly Cited
1996
Highly Cited
1996
Bcr/Abl is a chimeric oncogene that can cause both acute and chronic human leukemias. Bcr/Abl-encoded proteins exhibit elevated… (More)
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Highly Cited
1994
Highly Cited
1994
Apoptosis is the major form of cell death associated with the action of chemotherapeutic agents on tumor cells, and therefore the… (More)
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Highly Cited
1990
Highly Cited
1990
Oncogenic activation of the proto-oncogene c-abl in human leukemias occurs as a result of the addition of exons from the gene bcr… (More)
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