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Benapryzine

Known as: 2-(ethyl(propyl)amino)ethyl 2-hydroxy-2,2-diphenylacetate, Benaprizine 
 
National Institutes of Health

Papers overview

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2004
2004
N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride (LON 954) causes a reproducible rest tremor in mice, of rapid onset… Expand
  • table 2
Review
2003
Review
2003
BACKGROUND Anticholinergics were the first drugs available for the symptomatic treatment of Parkinson's disease and they are… Expand
1977
1977
Abstract The ability of various substances to antagonize the excitatory responses of cat cortical neurones to acetylcholine and L… Expand
1975
1975
A crossover clinical trial of benapryzine and trihexyphenidyl in ten parkinsonian patients during a four-month study is described… Expand
1974
1974
Abstract Benapryzine, a new antiparkinson agent, inhibits the uptake of dopamine into rat corpus striatum in vitro. The compound… Expand
1974
1974
  • Drug and therapeutics bulletin
  • 1974
  • Corpus ID: 12712226
In Parkinson’s disease there is an imbalance between the function of the cholinergic and dopaminergic neurones in the… Expand
1974
1974
SummaryIn an open study, benzapryzine, a new anticholinergic drug, in a daily dose of 200 mg. was found to be an effective… Expand
1973
1973
1 The pA2 anti‐acetylcholine activity in vitro for benapryzine was 6·55 compared with 902 for benzhexol. 2 In vivo, the anti… Expand
1973
1973
1 The effects of a potential anti‐Parkinson drug, benapryzine, have been compared with those of benzhexol, atropine and procaine… Expand
1971
1971
1. [14C]Benapryzine is absorbed after oral administration to the rat and is completely metabolized, the major route of excretion… Expand