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A recent lorcaserin trial investigated ‘the long-term cardiovascular and metabolic safety and efficacy of lorcaserin’ in subjects… Expand Serotonin (5-hydroxytryptamine; 5-HT) was identified in the mammalian brain in the 1950s. We now recognize brain 5-HT to… Expand Drugs for Weight Loss Pharmacologic treatment of obesity has been limited by modest efficacy, adverse effects, low adherence… Expand Lorcaserin, combined with diet and exercise, can be used to produce additional weight loss, although the effect on morbidity and… Expand Review Article Obesity has become a global problem, affecting countries which are developed and developing. One of the most… Expand Obesity is a risk factor for a wide range of conditions, including cardiovascular disease. Although lifestyle modifications… Expand The pharmacotherapy of obesity has historically recorded an overall poor safety and efficacy profile largely because of the… Expand In the U.S., obesity is prevalent in epidemic proportions, and rates continue to rise. Current data indicate that the combined… Expand New molecular entity: FDA approved Lorcaserin (Belviq, Arena Pharmaceuticals GMBH), as an adjunct to a reduced-calorie diet and… Expand