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Basal-Like Breast Carcinoma

Known as: Basal-Like Breast Cancer, Basal-Like Subtype of Breast Carcinoma 
A biologic subset of breast carcinoma defined by high expression of genes characteristic of basal epithelial cells, including KRT5 and KRT17, annexin… 
National Institutes of Health

Related topics

Related topics

12 relations
BreastEGFR Protein OverexpressionEGFR geneEpithelial Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Induction of N-Ras degradation by flunarizine-mediated autophagy
Ras GTPases are powerful drivers for tumorigenesis, but directly targeting Ras for treating cancer remains challenging. The… 
2014
2014
Disrupting the Interaction of BRD 4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer
Jian Shi,1,4 Yifan Wang,1,4,5 Lei Zeng,6 Yadi Wu,2,4 Jiong Deng,7 Qiang Zhang,6 Yiwei Lin,1,4 Junlin Li,1,4 Tiebang Kang,5 Min… 
2013
2013
Breast Cancer Subtypes and Previously Established Genetic Risk Factors: A Bayesian Approach
Background: Gene expression analyses indicate that breast cancer is a heterogeneous disease with at least five immunohistologic… 
2012
2012
Effect of anti-DR5 and chemotherapy on basal-like breast cancer
The purpose is to evaluate sensitivity of basal-like breast cancer to treatment with anti-DR5 alone and in combination with… 
2010
2010
Is ALDH1 a good method for definition of breast cancer stem cells?
Review
2010
Review
2010
Targeted chemotherapy? Platinum in BRCA1-dysfunctional breast cancer.
Although BRCA1-associated breast cancer is rare, comprising only 5% of breast cancers or fewer than 10,000 cases per year in the… 
2009
2009
Potential Predictive Markers of Benefit from Cetuximab in Metastatic Breast Cancer: An Analysis of Two Randomized Phase 2 Trials.
Background: Two randomized phase 2 studies investigated the efficacy of cetuximab (C), a mAb directed against EGFR, in metastatic… 
Highly Cited
2008
Highly Cited
2008
GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas.
The CpG island spanning the transcription start of the glutathione S-transferase P1 becomes methylated in a variety of human… 
2008
2008
Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component.
The basal-like subtype of breast cancer is associated with invasiveness, high rates of postsurgical recurrence, and poor… 
2007
2007
The Phosphoinositide-Dependent Kinase-1 Inhibitor 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide (OSU-03012) Prevents Y-Box Binding Protein-1 from Inducing…
The epidermal growth factor receptor (EGFR) is integral to basal-like and human epidermal growth factor receptor-2 (Her-2… 
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