BSc2118
National Institutes of Health
Papers overview
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Extralysosomal proteolysis is a multistep process involving the Ubiquitin- Proteasome System (UPS) and supplementary peptidases…
The ubiquitin/proteasome system is the major protein degradation pathway in eukaryotes with several key catalytic cores…
Background: Although the first generation of proteasome inhibitor bortezomib is very effective, the development of resistance…
The ubiquitin-proteasome complex has recently been identified as a novel therapeutic target, particularly in hematological…
The ubiquitin-proteasome pathway was recently identified as a promising new therapeutic target in cancer treatment. An increased…