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BSc2118

 
National Institutes of Health

Papers overview

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2016
2016
The ubiquitin/proteasome system is the major protein degradation pathway in eukaryotes with several key catalytic cores… Expand
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2015
2015
Since disturbance of angiogenesis predisposes to ischemic injuries, attempts to promote angiogenesis have been made to improve… Expand
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2015
2015
In view of its profound effect on cell survival and function, the modulation of the ubiquitin-proteasome-system has recently been… Expand
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2015
2015
Introduction of bortezomib, the first generation of proteasome inhibitor, has significantly improved the median overall survival… Expand
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2014
2014
Inhibition of the proteasome offers many therapeutic possibilities in inflammation as well as in neoplastic diseases. However… Expand
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Review
2012
Review
2012
Only a minority of stroke patients receive thrombolytic therapy. Therefore, new therapeutic strategies focusing on… Expand
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2010
2010
OBJECTIVES The ubiquitin-proteasome system emerged as a new therapeutic target in cancer treatment. The purpose of this study was… Expand
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2007
2007
The ubiquitin-proteasome complex has recently been identified as a novel therapeutic target, particularly in hematological… Expand
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2007
2007
Alzheimer's disease (AD) is the leading cause of dementia in the elderly, presenting itself clinically by progressive loss of… Expand
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2006
2006
The ubiquitin-proteasome pathway was recently identified as a promising new therapeutic target in cancer treatment. An increased… Expand
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