Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

BRCA1 Gene Mutation

Known as: BRCA1 Mutation, Mutation of the BRCA1 Gene 
A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA1 gene. Single nucleotide substitutions and small… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Breast cancer rates and median age of onset differ between Western Europe and North Africa. In Western populations, 5 to 10 % of… Expand
  • table 1
  • table 2
  • table 3
2005
2005
The authors report a prospective study comparing magnetic resonance imaging (MRI) with mammography for screening in women having… Expand
Highly Cited
2004
Highly Cited
2004
Mutations in breast cancer susceptibility genes, BRCA1 and BRCA2 account for more than 80% of hereditary breast and ovarian… Expand
  • figure 1
  • figure 3
2003
2003
Sixty high‐risk breast and/or ovarian cancer families from North‐Eastern Poland were screened for germline mutations in BRCA1… Expand
2000
2000
BRCA1 mutations have been identified in breast and ovarian cancer families from diverse ethnic backgrounds. We studied 17… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 3
Highly Cited
1999
Highly Cited
1999
BACKGROUND Breast carcinomas occurring in carriers of BRCA1 gene mutations may have a distinctly different pathway of molecular… Expand
1999
1999
Germ‐line mutations of the BRCA1 gene account for approximately half of the cases of hereditary breast/ovarian cancers. We have… Expand
Highly Cited
1997
Highly Cited
1997
BACKGROUND To define the incidence of BRCA1 mutations among patients seen in clinics that evaluate the risk of breast cancer, we… Expand
1997
1997
A predominant mutation within the BRCA1 predisposition gene, 185delAG, has been detected in about 1 % of the Ashkenazi population… Expand
1997
1997
Inherited mutations in the BRCA1 gene confer a predisposition to breast and ovarian cancer. We report the results of BRCA1… Expand