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BRCA1 Gene Mutation

Known as: BRCA1 Mutation, Mutation of the BRCA1 Gene 
A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA1 gene. Single nucleotide substitutions and small… 
National Institutes of Health

Related topics

Related topics

4 relations
BRCA1 SyndromeBRCA1 geneHereditary Prostate CarcinomaHigh Grade Ovarian Serous Adenocarcinoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Salivary Gland Function, Antioxidant Defence and Oxidative Damage in the Saliva of Patients with Breast Cancer: Does the BRCA1 Mutation Disturb the Salivary Redox Profile?
Oxidative stress plays a key role in breast cancer progression. However, little is still known about the relationship between the… 
Highly Cited
2008
Highly Cited
2008
BRCA1 mutations in Algerian breast cancer patients: high frequency in young, sporadic cases
Breast cancer rates and median age of onset differ between Western Europe and North Africa. In Western populations, 5 to 10 % of… 
2005
2005
Efficacy of magnetic resonance imaging and mammography for breast cancer screening in women with a familial or genetic predisposition
The authors report a prospective study comparing magnetic resonance imaging (MRI) with mammography for screening in women having… 
2003
2003
BRCA1 and BRCA2 mutation analysis in breast‐ovarian cancer families from northeastern Poland
Sixty high‐risk breast and/or ovarian cancer families from North‐Eastern Poland were screened for germline mutations in BRCA1… 
2001
2001
Mutagen sensitivity of human lymphoblastoid cells with a BRCA1 mutation in comparison to ataxia telangiectasia heterozygote cells
Our previous results indicated a close relationship between the presence of a BRCA1 mutation in lymphocytes and hypersensitivity… 
2000
2000
Evidence of a founder BRCA1 mutation in Scotland
BRCA1 mutations have been identified in breast and ovarian cancer families from diverse ethnic backgrounds. We studied 17… 
Highly Cited
1999
Highly Cited
1999
Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations.
BACKGROUND Breast carcinomas occurring in carriers of BRCA1 gene mutations may have a distinctly different pathway of molecular… 
Highly Cited
1999
Highly Cited
1999
Strong founder effects in BRCA1 mutation carrier breast cancer patients from Latvia
Germ‐line mutations of the BRCA1 gene account for approximately half of the cases of hereditary breast/ovarian cancers. We have… 
1997
1997
Could the 185 deIAG BRCA1 Mutation Be an Ancient Jewish Mutation?
A predominant mutation within the BRCA1 predisposition gene, 185delAG, has been detected in about 1 % of the Ashkenazi population… 
1997
1997
Differences in phenotypic expression of a new BRCA1 mutation in identical twins
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