BRCA1 Gene Mutation

Known as: BRCA1 Mutation, Mutation of the BRCA1 Gene 
A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA1 gene. Single nucleotide substitutions and small… (More)

Topic mentions per year

Topic mentions per year

1999-2017
02419992017

Papers overview

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Highly Cited
2013
Highly Cited
2013
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk… (More)
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2009
2009
Mutations in two major genes, BRCA1 and BRCA2, account for up to 30% of families with hereditary breast cancer. Unfortunately, in… (More)
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2008
2008
BACKGROUND Hormone therapy (HT) is commonly given to women to alleviate the climacteric symptoms associated with menopause. There… (More)
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2008
2008
Breast cancer rates and median age of onset differ between Western Europe and North Africa. In Western populations, 5 to 10 % of… (More)
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2007
2007
Modifying factors might theoretically determine whether a BRCA1 mutation carrier contracts breast or ovarian cancer. If so, one… (More)
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2006
2006
This study was undertaken with regard to the gonadotropin theory of ovarian cancer advocated in the literature and was designed… (More)
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2006
2006
Little is known about the impact of cancer genetic counseling and testing on health behaviors in racial and ethnic subgroups… (More)
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2001
2001
Background: In Jewish individuals of Ashkenazi (East European) decent, three predominant mutations, 185 delAG and 5382insC (BRCA1… (More)
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2000
2000
Previous results indicated that lymphoblastoid cell lines (LCL) with a BRCA1 mutation are hypersensitive to the chromosome… (More)
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