BRAF V600 Protein Variation

Known as: BRAF p.V600 Mutation, BRAF NP_004324.2:p.Val600Xxx, NP_004324.2:p.V600X 
A change in the valine at position 600 of the serine/threonine-protein kinase B-raf protein to another amino acid.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Neurodegenerative diseases can occur so early as to affect neurodevelopment. From a cohort of more than 2,000 consanguineous… (More)
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2012
2012
Constitutive activation of FLT3 by internal tandem duplication (ITD) is one of the most common molecular alterations in acute… (More)
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2009
2009
BRAF V600E is the predominantly occurring mutation of the cytoplasmic kinase BRAF, and, in colorectal cancer, its determination… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES To determine the mechanism of high-level resistance to fluoroquinolone antimicrobials in toxin-A-negative, toxin-B… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT The BRAF mutation may influence the expression patterns of molecular markers that are related to the development and… (More)
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Highly Cited
2004
Highly Cited
2004
To evaluate the mutational profiles associated with BRAF mutations in human melanoma, we have studied BRAF, RAS, PTEN, TP53… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Individuals with the cytochrome P450 (CYP) 2D6 intermediate metabolizer (IM) phenotype have low residual enzyme… (More)
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Highly Cited
2002
Highly Cited
2002
The canine disease, X-linked progressive retinal atrophy (XLPRA), is similar to human RP3, an X-linked form of retinitis… (More)
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Highly Cited
2002
Highly Cited
2002
The evolution of self-fertilization is associated with a large reduction in the effective rate of recombination and a… (More)
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1999
1999
Completing the molecular analysis of the six pal genes of the ambient pH signal transduction pathway in Aspergillus nidulans, we… (More)
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