BNP7787
National Institutes of Health
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BACKGROUND
Cisplatin and several related antineoplastic drugs used to treat many types of solid tumours are neurotoxic, and most…
Taxane and platinum drugs are important agents in the treatment of cancer and have shown activity against a variety of tumors…
Introduction: We investigated dose-dense docetaxel and cisplatin in patients with measurable non-small cell lung cancer in a…
In preclinical studies, BNP7787 (disodium 2,2′-dithio-bis-ethane sulphonate), the disulphide form of mesna, has demonstrated…
PurposeBNP7787 is a new chemoprotective agent presently under clinical investigation to protect against cisplatin-induced…
BackgroundBNP7787 (disodium 2,2′-dithio-bis-ethane sulfonate) was evaluated in a phase I clinical trial with paclitaxel and…
Sensitive, accurate, and precise assays are described to determine BNP7787 (disodium 2,2'-dithio-bis-ethane sulfonate) and its…
PurposeBNP7787 (2′,2′-dithio-bis-ethane sulfonate sodium) is a novel protector against cisplatin-induced toxicities. The…
Platinum-type drugs have proven to be valuable in the treatment of a variety of solid tumors, beginning with the commercial…