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BMS-470539

Known as: BMS470539 
National Institutes of Health

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Imidazoles

Papers overview

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2019
2019
The effects of BMS-470539 on lipopolysaccharide-induced acute lung injury
Background Overactivation of inflammatory cells, including macrophages and neutrophils, is associated with acute lung injury. BMS… 
2016
2016
Abstract PR109: The Role of Melanocortin Rc Agonist Bms-470539 On Lps Induced Inflammatory Cell Activation and Acute Lung Injury
Background & Objectives: Despite advances in the management of sepsis and acute respiratory distress syndrome, the mortality rate… 
2016
2016
AB0077 Targeting Synovial Fibroblasts with Melanocortin Drugs
Background The adrenocorticotropin hormone (ACTH) is a melanocortin (MC) peptide approved for the treatment of inflammatory… 
2015
2015
1046: MELANOCORTIN RC AGONIST BMS-470539 ATTENUATES LPS INDUCED NEUTROPHIL ACTIVATION & ACUTE LUNG INJURY
Crit Care Med 2015 • Volume 43 • Number 12 (Suppl.) a SSIE had a higher mean number of organ failures (2.97 ± 2.4 vs 1.65 ± 1.6… 
2014
2014
The role of melanocortin receptor agonist BMS-470539 on lipopolysaccharide-induced neutrophil activation and acute lung injury: 12AP3-3
2012
2012
Selected Melanocortin 1 Receptor Single-Nucleotide Polymorphisms Differentially Alter Multiple Signaling Pathways
The melanocortin 1 receptor (MC1R) is a highly polymorphic G protein-coupled receptor, which is known to modulate pigmentation… 
2006
2006
A selective small molecule agonist of the melanocortin‐1 receptor inhibits lipopolysaccharide‐induced cytokine accumulation and leukocyte infiltration in mice
It is well established that melanocortins are peptides that have potent anti‐inflammatory activity. Recent research has focused… 
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