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BMS 182874

Known as: BMS-182874 
National Institutes of Health

Papers overview

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2007
2007
Effects of endothelin-1 on fibroblasts from type 2 diabetic patients: Possible role in wound healing and tissue repair
Endothelin-1 (ET-1) promotes the contractile ability of fibroblasts, essential for wound closure and reconstitution of the dermis… 
2006
2006
Determination of endothelin antagonist BMS182874 in plasma by high-performance liquid chromatography.
A simple and rapid high performance liquid chromatography (HPLC) method was developed for the determination of BMS182874 (BMS) in… 
2005
2005
The endothelin receptor antagonist decreases ischemia/reperfusion-induced tumor necrosis factor production in isolated rat hearts.
1999
1999
Endothelin receptors in adult human and swine isolated ventricular cardiomyocytes.
1999
1999
Kinetics of endothelin-1 binding in the dog liver microcirculation in vivo.
Endothelin-1 (ET-1) is a 21-amino acid peptide produced by vascular endothelial cells that acts as a potent constrictor of… 
1999
1999
Haemodynamic influence and endothelin-1 plasma concentrations by selective or non-selective endothelin receptor antagonists in the pig in vivo.
In the present study the haemodynamical effects of endothelin (ET)-receptor antagonism was evaluated using selective and non… 
1998
1998
Hemodynamic effects of a selective endothelin--a receptor antagonist in deoxycorticosterone acetate-salt hypertensive rats.
The time-course changes in blood pressure (BP), cardiac output (CO), and total peripheral conductance (TPC) were investigated… 
1996
1996
Mutational analysis of the endothelin type A receptor (ETA): interactions and model of selective ETA antagonist BMS-182874 with putative ETA receptor binding cavity.
Endothelin (ET) receptor antagonism is a potential therapeutic intervention in the treatment of vascular diseases. To elucidate… 
1995
1995
A role for endothelin ETA receptors in regulation of renal function in spontaneously hypertensive rats.
1995
1995
Comparison of a novel ETA receptor antagonist and phosphoramidon in renal ischemia.
Infusion (0.46 mumol/kg/min) of the endothelin (ET)-converting-enzyme inhibitor, phosphoramidon (P), protected function and… 
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