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BMS 180448

Known as: BMS 180426, BMS-180426, BMS-180448 
National Institutes of Health

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4 relations

Broader (4)

BenzopyransCardiotonic AgentsGuanidinesVasodilator Agents

Papers overview

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2007
2007
Cardioprotective effects of bms-180448, a prototype mitokatp channel opener, and the role of salvage kinases, in the rat model of global ischemia and reperfusion heart injury
To investigate the involvement of reperfusion-induced salvage kinases (RISK) as possible signaling molecules for the… 
2007
2007
Disposition and Metabolism of [ 14 C ] Brasofensine in Rats , Monkeys , and Humans
Brasofensine is an inhibitor of the synaptic dopamine transporter. These studies were conducted to characterize the… 
2004
2004
[The effect of K(ATP)-channel activation on the electrical stability of myocardium in rats with postinfarction cardiosclerosis].
Opening of the ATP-dependent K-channels (K(ATP) channels) upon intravenous administration of the cardioselective activator BMS… 
2003
2003
Enhanced cardioprotection of the rat heart during hypothermic storage with combined Na+ - H+ exchange inhibition and ATP-dependent potassium channel activation.
2003
2003
Pharmacological characterization of vasorelaxant effects of BMS-180448, a novel cardioselective ATP-sensitive potassium channel opener, in rat aorta.
This study was designed to characterize vasorelaxant effects of BMS-180448 ((3S-trans)-N-(4-chlorophenyl)-N'-cyano-N"-(6-cyano-3… 
2001
2001
[Myocardial tolerance to arrhythmogenic exposure and pharmacological activation of K(ATP)-channels in rats].
The cardioselective KATP channel activator BMS 180448 (3 mg/kg) administered intravenously 15 min before the coronary artery… 
1999
1999
Cardioselective antiischemic ATP-sensitive potassium channel (K(ATP)) openers. 6. Effect of modifications at C6 of benzopyranyl cyanoguanidines.
The effect on potency and selectivity of modifications at the C6 position of the cardioprotective K(ATP) opener BMS-180448 (2) is… 
1996
1996
The novel cardioprotective agent BMS-180448 activates a potassium conductance in cardiac and vascular smooth muscle
The goal of the present study was to further characterize the effects of the novel cardioprotective agent BMS-180448 on potassium… 
1996
1996
Cardioprotection associated with preconditioning in the anesthetized ferret
The cardioprotective effect of ischemic preconditioning (PC) was investigated in the anesthetized ferret model of myocardial… 
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