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BMP2 protein, human
Known as:
Bone Morphogenetic Protein 2
, BMP-2 protein, human
, BMP-2
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Bone morphogenetic protein 2 (396 aa, ~45 kDa) is encoded by the human BMP2 gene. This protein plays a role in cartilage and bone formation.
National Institutes of Health
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Related topics
Related topics
29 relations
ALK Pathway
BMP2 gene
Bone Morphogenetic Protein Gene
Brain
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Broader (1)
bone morphogenetic protein 2
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
LncRNA MSC-AS1 promotes osteogenic differentiation and alleviates osteoporosis through sponging microRNA-140-5p to upregulate BMP2.
Naidong Zhang
,
Xinyu Hu
,
+4 authors
Zhihui Huang
Biochemical and Biophysical Research…
2019
Corpus ID: 202760764
Highly Cited
2010
Highly Cited
2010
Tensile Strain as a Regulator of Mesenchymal Stem Cell Osteogenesis
E. M. Kearney
,
E. Farrell
,
P. Prendergast
,
V. Campbell
Annals of Biomedical Engineering
2010
Corpus ID: 13901016
A role for mechanical stimulation in the control of cell fate has been proposed and mechanical conditioning of mesenchymal stem…
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Review
2009
Review
2009
BMP2 signaling in bone development and repair.
V. Rosen
Cytokine & growth factor reviews
2009
Corpus ID: 207072153
Highly Cited
2007
Highly Cited
2007
Murine and Chicken Chondrocytes Regulate Osteoclastogenesis by Producing RANKL in Response to BMP2
M. Usui
,
L. Xing
,
+4 authors
B. Boyce
Journal of Bone and Mineral Research
2007
Corpus ID: 35689959
Chondrocytes express RANKL, but their role in osteoclastogenesis is not clear. We report that hypertrophic chondrocytes induce…
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Highly Cited
2006
Highly Cited
2006
BMP is an important regulator of proepicardial identity in the chick embryo.
J. Schlueter
,
J. Männer
,
T. Brand
Developmental Biology
2006
Corpus ID: 29845119
Highly Cited
2005
Highly Cited
2005
Combined effects of TGFβ1 and BMP2 in serum-free chondrogenic differentiation of mesenchymal stem cells induced hyaline-like cartilage formation
W. Toh
,
Hua Liu
,
B. Heng
,
A. J. Rufaihah
,
C. P. Ye
,
T. Cao
Growth Factors
2005
Corpus ID: 3194431
This study investigated the effects of TGFβ1, BMP2 or a combination of both on the chondrogenic differentiation of mesenchymal…
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Highly Cited
2005
Highly Cited
2005
Runx2 regulates FGF2‐induced Bmp2 expression during cranial bone development
K. Choi
,
Hyun-Jung Kim
,
+8 authors
H. Ryoo
Developmental Dynamics
2005
Corpus ID: 25468597
Calvarial bone is formed by the intramembranous bone‐forming process, which involves many signaling molecules. The constitutive…
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Highly Cited
2004
Highly Cited
2004
Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia
M. Horiki
,
T. Imamura
,
+7 authors
N. Tsumaki
Journal of Cell Biology
2004
Corpus ID: 545395
Biochemical experiments have shown that Smad6 and Smad ubiquitin regulatory factor 1 (Smurf1) block the signal transduction of…
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Highly Cited
2003
Highly Cited
2003
BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels.
K. Waite
,
C. Eng
Human Molecular Genetics
2003
Corpus ID: 15490780
The tumour suppressor gene PTEN encodes a dual-specificity phosphatase that recognizes protein and phosphatidylinositiol…
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Highly Cited
2001
Highly Cited
2001
Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse.
Ying Ying
,
G. Zhao
Developmental Biology
2001
Corpus ID: 23878011
The primordial germ cells (PGCs) of the mouse are derived from proximal epiblast cells that are adjacent to the extraembryonic…
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