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BMI1 gene

Known as: BMI1 Polycomb Ring Finger Oncogene Gene, BMI1 proto-oncogene, polycomb ring finger, BMI1 
This gene plays a role in transcriptional regulation and embryonic development.
National Institutes of Health

Related topics

Related topics

6 relations
B-Cell LymphomasBMI1 protein, humanBMI1 wt AlleleTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
MicroRNA-203 inhibits cellular proliferation and invasion by targeting Bmi1 in non-small cell lung cancer.
MicroRNAs are proposed to serve vital functions in the regulation of tumor progression and invasion. However, the expression… 
2015
2015
Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Epigenetic dysregulation is involved in the initiation and progression of many epithelial cancers. BMI1, a component of the… 
2015
2015
Bmi1 Essentially Mediates Podocalyxin-Enhanced Cisplatin Chemoresistance in Oral Tongue Squamous Cell Carcinoma
Oral tongue squamous cell carcinoma (OTSCC) is one of the most common head and neck cancers. Innate or acquired resistance to… 
Highly Cited
2013
Highly Cited
2013
Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression.
Cancer-initiating cells comprise a heterogeneous population of undifferentiated cells with the capacity for self-renewal and high… 
2012
2012
Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells.
2012
2012
Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL-initiating cells.
The characterization and targeting of Philadelphia chromosome positive (Ph(+)) acute lymphoblastic leukemia (ALL)-initiating… 
Highly Cited
2011
Highly Cited
2011
Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes
Polycomb group gene Bmi1 functions as a tumor suppressor in myelofibrosis. 
2011
2011
Bmi1 regulates cell fate via tumor suppressor WWOX repression in small‐cell lung cancer cells
Mortality from lung cancer is important worldwide. Recently, epigenetic aberration of lung cancer, not only genomic DNA… 
Highly Cited
2010
Highly Cited
2010
Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf‐dependent and ‐independent manners in Mice
We previously reported that forced expression of Bmi1 (B lymphoma Moloney murine leukemia virus insertion region 1 homolog) in… 
Highly Cited
2006
Highly Cited
2006
E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells.
The Polycomb group gene Bmi1 is essential for the proliferation of neural and hematopoietic stem cells. Much remains to be… 
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