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BKT140
Known as:
BL-8040
, CXCR4 Antagonist BL-8040
An orally bioavailable inhibitor of CXC Chemokine Receptor 4 (CXCR4) with potential antineoplastic activity. CXCR4 antagonist BL-8040 selectively…
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National Institutes of Health
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Related topics
Related topics
2 relations
NCIt Antineoplastic Agent Terminology
Broader (1)
Oligopeptides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The CXCR4 Antagonist, BL8040, Is Highly Active Against Human T-ALL in Preclinical Models
Jun Xia
,
M. Jotte
,
+6 authors
D. Link
Blood
2018
Corpus ID: 86603318
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy that accounts for 10-15% of pediatric and…
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2014
2014
Novel CXCR4 Antagonist Enters Clinical Testing for CML
D. Levitan
2014
Corpus ID: 182516643
A novel agent known as BL-8040 will enter phase I/II testing for the treatment of chronic myeloid leukemia, according to…
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2014
2014
Cancer Therapy : Clinical The High-Af fi nity CXCR 4 Antagonist BKT 140 Is Safe and Induces a Robust Mobilization of Human CD 34 þ Cells in Patients with Multiple Myeloma
A. Peled
,
Michal Abraham
,
+14 authors
A. Nagler
2014
Corpus ID: 46330062
Purpose:CXCR4 plays an important role in the retention of stem cells within the bonemarrow. BKT140 (4F-benzoyl-TN14003) is a 14…
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