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BIO 1211

Known as: BIO-1211 
National Institutes of Health

Related topics

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1 relation

Broader (1)

Oligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
[Inhibitory effects of BIO-1211 on bronchoconstriction and neutrophil adhesion in rats].
OBJECTIVE To determine the inhibitory effects of BIO-1211, a very late antigen-4 (vla-4) antagonist, on bronchoconstriction and… 
2004
2004
Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin: From a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses
The very late antigen-4 (VLA-4), also known as integrin alpha4beta1, is expressed on monocytes, T- and B-lympohocytes, basophils… 
Review
2004
Review
2004
The discovery and potential of N-sulfonylated dipeptide VLA-4 antagonists.
Through a directed screening of a combinatorial library containing carboxylic acids, N-sulfonylated dipeptides were identified as… 
2003
2003
[Effects of BIO-1211 on eosinophil chemotaxis, recruitment and mediator release].
OBJECTIVE To study the effects of very late antigen(VLA) antagonist BIO-1211 on eosinophil chemotaxis, recruitment and mediator… 
2000
2000
A small-molecule, tight-binding inhibitor of the integrin alpha(4)beta(1) blocks antigen-induced airway responses and inflammation in experimental asthma in sheep.
The leukocyte integrin very late antigen-4 (alpha(4)beta(1), CD49d/CD29) is an adhesion receptor that plays an important role in… 
2000
2000
BIO-1211 (Biogen).
  • G. T. Bolger
  • IDrugs : the investigational drugs journal
  • 2000
  • Corpus ID: 30706922
Biogen, in collaboration with Merck & Co, is developing late activator VLA-4 (alpha4beta1) integrin antagonists for the potential… 
2000
2000
BIO-1211 (Biogen).
Biogen, in collaboration with Merck & Co, is developing late activator VLA-4 (alpha4beta1) integrin antagonists for the potential… 
Highly Cited
1999
Highly Cited
1999
Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses.
Integrin alpha4beta1 mediates leukocyte recruitment, activation, mediator release, and apoptosis inhibition, and it plays a… 
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