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BIIB022

Known as: Anti-IGF-1R Recombinant Monoclonal Antibody BIIB022, BIIB-022 
A recombinant, human monoclonal antibody directed against the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity… 
National Institutes of Health

Papers overview

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2014
2014
SummaryPurpose The IGF-1R signaling pathway has been implicated in multiple cancers as important for cell survival, proliferation… 
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Review
2012
Review
2012
The type 1 insulin-like growth factor receptor (IGF-1R) and its downstream signaling components have become increasingly… 
Review
2011
Review
2011
  • E. Ozkan
  • Molecular and Cellular Endocrinology
  • 2011
  • Corpus ID: 37296132
Cancer database analysis indicates that prostate cancer is one of the most seen cancers in men meanwhile composing the leading… 
2010
2010
2612 Background: The IGF pathway is believed to play a key role in the pathogenesis of several tumors. BIIB022 is a human… 
Review
2009
Review
2009
The insulin-like growth factor 1 receptor (IGF-1R) and its associated signalling system has provoked considerable interest over… 
2009
2009
Biogen Idec has expanded its agreement to discover additional antibody products using Dyax’s phage display drug discovery… 
2008
2008
4002 Antibodies to IGF-1R as inhibitors of PI3K/AKT survival pathway have shown evidence of objective responses in early clinical… 
2007
2007
B210 Antibodies targeting human type I insulin-like growth factor receptor (IGF-1R) as inhibitors of tumor survival pathway have…