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BIIB022

Known as: Anti-IGF-1R Recombinant Monoclonal Antibody BIIB022, BIIB-022 
A recombinant, human monoclonal antibody directed against the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity… Expand
National Institutes of Health

Papers overview

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2014
2014
SummaryPurpose The IGF-1R signaling pathway has been implicated in multiple cancers as important for cell survival, proliferation… Expand
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Review
2012
Review
2012
The type 1 insulin-like growth factor receptor (IGF-1R) and its downstream signaling components have become increasingly… Expand
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Review
2011
Review
2011
  • E. E. Ozkan
  • Molecular and Cellular Endocrinology
  • 2011
  • Corpus ID: 37296132
Cancer database analysis indicates that prostate cancer is one of the most seen cancers in men meanwhile composing the leading… Expand
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2010
2010
2612 Background: The IGF pathway is believed to play a key role in the pathogenesis of several tumors. BIIB022 is a human… Expand
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2009
2009
Biogen Idec has expanded its agreement to discover additional antibody products using Dyax’s phage display drug discovery… Expand
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Review
2009
Review
2009
The insulin-like growth factor 1 receptor (IGF-1R) and its associated signalling system has provoked considerable interest over… Expand
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2008
2008
4002 Antibodies to IGF-1R as inhibitors of PI3K/AKT survival pathway have shown evidence of objective responses in early clinical… Expand
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2007
2007
B210 Antibodies targeting human type I insulin-like growth factor receptor (IGF-1R) as inhibitors of tumor survival pathway have… Expand
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