Skip to search formSkip to main contentSkip to account menu

BH4 Domain

BH4 is present only in the amino-terminal regions of pro-survival family bcl-2 members and is essential for the anti-apoptotic function, although… 
National Institutes of Health

Related topics

Related topics

1 relation
Bcl-2-Related Ovarian Killer Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Venetoclax Resistance in Mantle Cell Lymphoma Is Mediated By BCL-XL and Can be Circumvent By Inhibiting the BH4 Domain of BCL-2
Apoptosis is controlled by the expression levels and interplay of pro- and anti-apoptotic BCL-2 family proteins. The specific BCL… 
2018
2018
A double point mutation at residues Ile14 and Val15 of Bcl‐2 uncovers a role for the BH4 domain in both protein stability and function
B‐cell lymphoma 2 (Bcl‐2) protein is the archetype apoptosis suppressor protein. The N‐terminal Bcl‐2‐homology 4 (BH4) domain of… 
2013
2013
Lysine dimethylation in the BH4 domain of Bcl-2 and functional significance (P1306)
Bcl-2 is an anti-apoptotic protein that can protect developing and mature T cells against a variety of apoptotic signals. The… 
2012
2012
The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond
Anti-apoptotic Bcl-2-family members not only neutralize pro-apoptotic proteins but also directly regulate intracellular Ca2… 
2011
2011
Systemic delivery of BH4 anti-apoptotic peptide using CPPs prevents cardiac ischemia-reperfusion injuries in vivo.
2007
2007
Oligomerization of BH4-truncated Bcl-x(L) in solution.
2006
2006
Fast and quantitative recovery of hydrophobic and amphipathic peptides after incorporation into phospholipid membranes.
A new method that allows fast and quantitative recovery of hydrophobic or amphipathic peptides, or both, after their intimate… 
2003
2003
The role of various Bcl‐2 domains in the anti‐proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain
Abstract. Reduced cell proliferation and increased levels of cellular glutathione (GSH) are characteristic for cells that… 
2000
2000
BH 4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
BIOCHEMISTRY. For the article ‘‘BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and… 
Highly Cited
1999
Highly Cited
1999
Linkage of the BH4 Domain of Bcl-2 and the Nuclear Factor κB Signaling Pathway for Suppression of Apoptosis*
Nuclear factor (NF) κB is a ubiquitously expressed transcription factor whose function is regulated by the cytoplasmic inhibitor… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)