Lucie Khemtemourian

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Human islet amyloid polypeptide (hIAPP) is the major component of the amyloid deposits found in the pancreatic islets of patients with type 2 diabetes mellitus (T2DM). Mature hIAPP, a 37-aa peptide, is natively unfolded in its monomeric state but forms islet amyloid in T2DM. In common with other misfolded and aggregated proteins, amyloid formation involves(More)
The formation of protein amyloid deposits is associated with major human diseases including Alzheimer's disease, Parkinson's disease, Spongiform Encephalopathy, and type 2 diabetes mellitus (T2DM). Today, 382 million people live with diabetes. Diabetes is on the rise all over the world and countries are struggling to keep pace treating all these patients.(More)
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