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Objective: To evaluate the mechanism of action of dimethylfumarate (DMF), a novel oral therapeutic for the treatment of multiple… Expand Inflammation and oxidative stress are thought to promote tissue damage in multiple sclerosis. Thus, novel therapeutics enhancing… Expand Importance of the field: One of the disadvantages of currently available disease-modifying drugs (DMDs) for multiple sclerosis… Expand Disease-modifying therapies (DMTs) for treating multiple sclerosis (MS) are entering a period of rapid and profound change that… Expand BACKGROUND
Oral fumarate (BG00012) might have dual anti-inflammatory and neuroprotective effects. Our aim was to assess the… Expand