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BCX1777

Known as: BCX-1777 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
For the past few years more and more new cytotoxic agents active in the treatment of hematological malignancies have been… 
Review
2008
Review
2008
Recently, the search for more effective and safer antineoplastic agents has led to synthesis and introduction into preclinical… 
Review
2006
Review
2006
The purine nucleoside analogs (PNA) form an important group of cytotoxic drugs active in the treatment of neoplastic and… 
2006
2006
Background: Forodesine, a potent, rationally designed purine nucleoside phosphorylase inhibitor, has shown clinical activity in T… 
2006
2006
Abstract Background: Forodesine is a potent, rationally designed purine nucleoside phosphorylase (PNP) inhibitor that is orally… 
Highly Cited
2005
Highly Cited
2005
The discovery of purine nucleoside phosphorylase (PNP) deficiency and T lymphocytopenia suggested that inhibition of this enzyme… 
2004
2004
The profound suppression of T-cell immunity seen in patients with an inherited PNP deficiency supports the potential application… 
Highly Cited
2003
2003
2003
Reduction of the pentavalent arsenate (AsV) to the thiol-reactive arsenite (AsIII) toxifies this environmentally prevalent form… 
Highly Cited
2001