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BCR Downstream Signaling 1 Protein

Known as: STAP-1, BCR Downstream Signaling 1, BRDG1 
BCR Downstream Signaling 1, encoded by BRDG1 gene, functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor… Expand
National Institutes of Health

Related topics

Related topics

11 relations
Docking -molecular interactionHomo sapiensPlasma membranePleckstrin Homology Domains
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Papers overview

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2018
2018
Role of Signal Transducing Adaptor Protein-1 (STAP-1) in Chronic Myelogenous Leukemia Stem Cells
 
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2017
2017
Role of Signal Transducing Adaptor Protein (STAP) Family in Chronic Myelogenous Leukemia
Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disorder that is caused by hematopoietic stem cells expressing… Expand
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Review
2014
Review
2014
Adaptor protein STAP-2 modulates cellular signaling in immune systems.
  • Yuichi Sekine
  • Biological & pharmaceutical bulletin
  • 2014
    • Corpus ID: 24392686
Signal-transducing adaptor protein-2 (STAP-2) is a recently identified adaptor protein that contains a pleckstrin homology (PH… Expand
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Highly Cited
2010
Highly Cited
2010
Loops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets
Selective blocking of binding pockets by surface loops defines the specificity of a phosphotyrosine-binding domain. Picking the… Expand
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Highly Cited
2008
Highly Cited
2008
Defining the Specificity Space of the Human Src Homology 2 Domain*S
Src homology 2 (SH2) domains are the largest family of interaction modules encoded by the human genome to recognize tyrosine… Expand
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2005
2005
Physical and Functional Interactions between STAP-2/BKS and STAT5*
Signal-transducing adaptor protein family of proteins (STAPs), which currently contains two members, are proposed to be adaptor… Expand
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2002
2002
Functional analysis of docking protein,BRDG1 in murine B cells
 
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2001
2001
Isoform-dependent interaction of BRDG1 with Tec kinase.
Tec is the prototype of an emerging family of protein-tyrosine kinases. Tec and Btk, another member of this family, together… Expand
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2000
2000
Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.
To identify the novel substrate of c-kit which is important for hematopoietic stem cell self-renewal or differentiation, CD34-low… Expand
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1999
1999
Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase.
Tec, Btk, Itk, Bmx, and Txk constitute the Tec family of protein tyrosine kinases (PTKs), a family with the distinct feature of… Expand
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