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BCLAF1 gene
Known as:
BTF
, KIAA0164
, BCL2 associated transcription factor 1
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Human BCLAF1 wild-type allele is located within 6q22-q23 and is approximately 33 kb in length. This allele, which encodes Bcl-2-associated…
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National Institutes of Health
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Related topics
Related topics
6 relations
BCLAF1 protein, human
Homo sapiens
Positive Regulation of Apoptosis
Transcriptional Regulation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export
Jekaterina Vohhodina
,
E. M. Barros
,
+7 authors
K. Savage
Nucleic acids research
2017
Corpus ID: 52810215
Abstract mRNA splicing and export plays a key role in the regulation of gene expression, with recent evidence suggesting an…
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Review
2015
Review
2015
The RNA Splicing Response to DNA Damage
L. Shkreta
,
B. Chabot
Biomolecules
2015
Corpus ID: 1972902
The number of factors known to participate in the DNA damage response (DDR) has expanded considerably in recent years to include…
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Highly Cited
2014
Highly Cited
2014
BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells.
Xuexia Zhou
,
Xuebing Li
,
+7 authors
Y. Feng
Nature communications
2014
Corpus ID: 33837211
Bcl-2-associated transcription factor 1 (BCLAF1) is known to be involved in multiple biological processes. Although several…
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Highly Cited
2013
Highly Cited
2013
Control of autophagic cell death by caspase-10 in multiple myeloma.
Laurence Lamy
,
V. Ngo
,
+8 authors
L. Staudt
Cancer cell
2013
Corpus ID: 5141462
We performed a loss-of-function RNA interference screen to define therapeutic targets in multiple myeloma, a genetically diverse…
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Highly Cited
2013
Highly Cited
2013
Discovery of a chemical probe for the L3MBTL3 methyl-lysine reader domain
L. James
,
D. Barsyte-Lovejoy
,
+21 authors
Stephen V Frye
Nature chemical biology
2013
Corpus ID: 18904203
We describe the discovery of UNC1215, a potent and selective chemical probe for the methyl-lysine (Kme) reading function of…
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Highly Cited
2013
Highly Cited
2013
Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle*
K. Horiuchi
,
T. Kawamura
,
+4 authors
T. Hamakubo
The Journal of Biological Chemistry
2013
Corpus ID: 23137730
Background: WTAP is a ubiquitously expressed nuclear protein that is required for mammalian early embryo development and cell…
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Highly Cited
2007
Highly Cited
2007
Systematic Discovery of In Vivo Phosphorylation Networks
R. Linding
,
L. Jensen
,
+18 authors
T. Pawson
Cell
2007
Corpus ID: 15432963
Protein kinases control cellular decision processes by phosphorylating specific substrates. Thousands of in vivo phosphorylation…
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2007
2007
Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage.
H. Liu
,
Z. Lu
,
Y. Miki
,
K. Yoshida
Molecular and cellular biology
2007
Corpus ID: 35633114
Expression of the TP53 tumor suppressor is tightly controlled for its ability to function as a critical regulator of cell growth…
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Highly Cited
2004
Highly Cited
2004
Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy.
T. Haraguchi
,
J. Holaska
,
+5 authors
Y. Hiraoka
European journal of biochemistry
2004
Corpus ID: 9866921
Loss of functional emerin, a nuclear membrane protein, causes X-linked recessive Emery-Dreifuss muscular dystrophy. In a yeast…
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Highly Cited
1999
Highly Cited
1999
Btf, a Novel Death-Promoting Transcriptional Repressor That Interacts with Bcl-2-Related Proteins
G. M. Kasof
,
L. Goyal
,
E. White
Molecular and Cellular Biology
1999
Corpus ID: 25958197
ABSTRACT The adenovirus E1B 19,000-molecular-weight (19K) protein is a potent inhibitor of apoptosis and cooperates with E1A to…
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