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BCLAF1 gene

Known as: BTF, KIAA0164, BCL2 associated transcription factor 1 
Human BCLAF1 wild-type allele is located within 6q22-q23 and is approximately 33 kb in length. This allele, which encodes Bcl-2-associated… Expand
National Institutes of Health

Related topics

Related topics

6 relations
BCLAF1 protein, humanHomo sapiensPositive Regulation of ApoptosisTranscriptional Regulation
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export
Abstract mRNA splicing and export plays a key role in the regulation of gene expression, with recent evidence suggesting an… Expand
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Review
2015
Review
2015
The RNA Splicing Response to DNA Damage
The number of factors known to participate in the DNA damage response (DDR) has expanded considerably in recent years to include… Expand
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Highly Cited
2014
Highly Cited
2014
BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells.
Bcl-2-associated transcription factor 1 (BCLAF1) is known to be involved in multiple biological processes. Although several… Expand
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Highly Cited
2013
Highly Cited
2013
Control of autophagic cell death by caspase-10 in multiple myeloma.
We performed a loss-of-function RNA interference screen to define therapeutic targets in multiple myeloma, a genetically diverse… Expand
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Highly Cited
2013
Highly Cited
2013
Discovery of a chemical probe for the L3MBTL3 methyl-lysine reader domain
We describe the discovery of UNC1215, a potent and selective chemical probe for the methyl-lysine (Kme) reading function of… Expand
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Highly Cited
2013
Highly Cited
2013
Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle*
Background: WTAP is a ubiquitously expressed nuclear protein that is required for mammalian early embryo development and cell… Expand
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Highly Cited
2007
Highly Cited
2007
Systematic Discovery of In Vivo Phosphorylation Networks
Protein kinases control cellular decision processes by phosphorylating specific substrates. Thousands of in vivo phosphorylation… Expand
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2007
2007
Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage.
Expression of the TP53 tumor suppressor is tightly controlled for its ability to function as a critical regulator of cell growth… Expand
Highly Cited
2004
Highly Cited
2004
Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy.
Loss of functional emerin, a nuclear membrane protein, causes X-linked recessive Emery-Dreifuss muscular dystrophy. In a yeast… Expand
Highly Cited
1999
Highly Cited
1999
Btf, a Novel Death-Promoting Transcriptional Repressor That Interacts with Bcl-2-Related Proteins
ABSTRACT The adenovirus E1B 19,000-molecular-weight (19K) protein is a potent inhibitor of apoptosis and cooperates with E1A to… Expand
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