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BBSome

Known as: Bardet-Biedl syndrome complex, Bardet-Biedl syndrome complex location 
A protein complex that associates with the primary cilium and is involved in cilium biogenesis; consists of seven conserved proteins: BBS1, BBS2… 
National Institutes of Health

Papers overview

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2020
2020
Moving proteins along in the cilium
The structures of the bovine and human BBSome reveal that a conformational change is required to recruit the complex to the… 
2020
2020
The absence of BBSome function decreases synaptogenesis and causes ectopic synapse formation in the retina
Photoreceptors possess ribbon synapses distinct from the conventional synapses in the brain. Little is known about the function… 
2019
2019
Smooth Muscle Cell-Specific Disruption of the BBSome Causes Vascular Dysfunction.
The BBSome-a complex consisting of 8 Bardet-Biedl syndrome proteins-is involved in the regulation of various cellular processes… 
2019
2019
Abstract P3001: Disruption of Endothelial BBSome Causes Vascular Dysfunction and Hepatosteatosis
Almost every single cell in the human body possesses primary cilium. The primary cilium function as a sensor of blood flow and… 
Review
2018
Review
2018
[Progress of research on Bardet-Biedl syndrome].
  • Peng ZengT. Shen
  • Zhonghua yi xue yi chuan xue za zhi = Zhonghua…
  • 2018
  • Corpus ID: 4894907
Bardet-Biedl syndrome (BBS) is a rare genetic disease caused by ciliary structure abnormality or dysfunction. To date, more than… 
2017
2017
Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella
ABSTRACT Intraflagellar transport (IFT) particles are composed of polyprotein complexes IFT-A and IFT-B as well as cargo adaptors… 
2015
2015
A Splice Variant of Bardet-Biedl Syndrome 5 (BBS5) Protein that Is Selectively Expressed in Retina
Purpose Bardet-Biedl syndrome is a complex ciliopathy that usually manifests with some form of retinal degeneration, amongst… 
2013
2013
Hypoxia takes invadopodia up a Notch
![Figure][1] The increase in actin-rich puncta shows that a cancer cell line forms more invadopodia in low-oxygen conditions… 
2012
2012
Ion channels boost axonal injury in multiple sclerosis
In neuroinflammatory diseases such as multiple sclerosis, ion channels may fan the embers of neurodegeneration. A new study shows… 
2010
2010
ROLE OF PHOSPHATIDYLINOSITOL METABOLISM IN RENAL EPITHELIAL MEMBRANE TRAFFIC
Phosphatidylinositol (PI) and its phosphorylated derivatives, phosphatidylinositides (PIPs), are versatile cellular regulators… 
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