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BBR3610

National Institutes of Health

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Organoplatinum Compounds

Papers overview

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2011
2011
Combined action of the dinuclear platinum compound BBR3610 with the PI3‐K inhibitor PX‐866 in glioblastoma
Polynuclear platinum compounds are more effective at killing glioblastoma cells than cisplatin, work by a different mechanism… 
2011
2011
Solution studies of dinuclear polyamine-linked platinum-based antitumour complexes.
The aquation profiles of two novel dinuclear polyamine-linked, platinum-based antitumour complexes [{trans-PtCl((15)NH(3))(2)}(2… 
2010
2010
The polynuclear platinum BBR3610 induces G2/M arrest and autophagy early and apoptosis late in glioma cells.
BBR3610 is a polynuclear platinum compound, in which two platinums are linked by a spermine-like linker, and studies in a variety… 
2007
2007
Low-Dose BBR3610 Toxicity in Colon Cancer Cells Is p53-Independent and Enhanced by Inhibition of Epidermal Growth Factor Receptor (ERBB1)-Phosphatidyl Inositol 3 Kinase Signaling
We have examined the mechanisms by which the multinuclear platinum chemotherapeutic BBR3610 kills human colon cancer cells… 
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