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BBR 2778

Known as: BBR-2778, BBR2778 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Pixantrone Dimaleatepixantrone

Papers overview

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2010
2010
Abstract 3576: Pixantrone is chemically and mechanistically related to mitoxantrone (Mito) and doxorubicin (Dox) but lacks their iron binding properties and myocyte toxicity in vitro
The anthracyclines (Dox), anthracenediones (Mito) and anthrapyrazoles (losoxantrone) are all intercalating topoisomerase II… 
Review
2009
Review
2009
Pixantrone maleate for non-Hodgkin's lymphoma.
Pixantrone (BBR-2778) is a novel aza-anthracenedione anthracycline derivative developed by Cell Therapeutics Incorporated, WA… 
2008
2008
Pixantrone (BBR2778) Reduces the Severity of Experimental Autoimmune Myasthenia Gravis in Lewis Rats1
Pixantrone (BBR2778) (PIX) and mitoxantrone share the same mechanism of action because both drugs act as DNA intercalants and… 
2005
2005
Corrigendum to “Pixantrone (BBR2778): A new immunosuppressant in multiple sclerosis with a low cardiotoxicity” [J Neurol Sci 223 (2004) 81–86]
2004
2004
A phase I/II trial of BBR-2778 (pixantrone), methylprednisolone, cisplatin, and cytosine arabinoside (BSHAP) in relapsed/refractory aggressive non-Hodgkin's lymphoma (NHL).
6590 Background: BBR-2778 (Pixantrone) is a novel aza-anthacenedione DNA intercalator with anti-tumor synergy with cisplatin, no… 
2004
2004
Preliminary Phase II Study Results of BBR2778 in Combination with Cyclophosphamide, Vincristine, and Prednisone in Patients with Relapsed Aggressive Non-Hodgkin’s Lymphoma.
Background: Pixantrone (BBR 2778) is a novel aza-anthracenedione with superior activity compared to doxorubicin and mitoxantrone… 
2002
2002
Efficacy of a novel non-cardiotoxic anthracenedione (BBR2778) in chronic relapsing experimental autoimmune encephalomyelitis
2001
2001
Efficacy of a novel non-cardiotoxic aza-anthracenedione (BBR2778) in acute EAE
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