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pixantrone

Known as: 6,9-Bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione, 6,9-AEA-BIQDO, 5,8-bis((2-aminoethyl)amino)-2-aza-anthracene-9,10-dione 
A synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Abstract Vesicles in volcanic rocks are frozen records of degassing processes in magmas. For this reason, their sizes, spatial… Expand
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Review
2006
Review
2006
The G-protein-coupled receptor (GPCR)-kinase-interacting proteins 1 and 2 (GIT1 and GIT2) are ubiquitous multidomain proteins… Expand
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Highly Cited
2005
Highly Cited
2005
Three of seven recently identified genes mutated in nonsyndromic mental retardation are involved in Rho family signaling. Two of… Expand
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Highly Cited
2005
Highly Cited
2005
It has been demonstrated that electrical stimulation of the retina can produce visual percepts in blind patients suffering from… Expand
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Highly Cited
2003
Highly Cited
2003
Efficient chemotaxis requires directional sensing and cell polarization. We describe a signaling mechanism involving G beta gamma… Expand
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Highly Cited
2002
Highly Cited
2002
This paper presents a measurement of the angular power spectrum of the cosmic microwave background from l = 75 to l = 1025 (~10… Expand
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Highly Cited
2001
Highly Cited
2001
Mutations in dpix were recovered from a large-scale screen in Drosophila for genes that control synaptic structure. dpix encodes… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT The p21-activated kinase PAK is targeted to focal complexes (FCs) through interactions with the SH3 domains of the PAK… Expand
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Highly Cited
1999
Highly Cited
1999
Paxillin is a focal adhesion adaptor protein involved in the integration of growth factor- and adhesion-mediated signal… Expand
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Highly Cited
1998
Highly Cited
1998
The PAK family of kinases are regulated through interaction with the small GTPases Cdc42 and Rac1, but little is known of the… Expand
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