BB-83698

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2007
012320022007

Papers overview

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2008
2008
BB-83698 is a first potent inhibitor of peptide deformylase in this novel class to enter clinical trials. In this study… (More)
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2007
2007
The relatively rapid development of microbial resistance after the entry of every new antimicrobial into the marketplace… (More)
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Review
2005
Review
2005
The metalloenzyme peptide deformylase (PDF) represents one of the most promising bacterial targets in the search for novel mode… (More)
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Review
2005
Review
2005
Peptide deformylase (PDF) is an attractive target for antibacterial drug discovery. Progress in the biological characterisation… (More)
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Review
2005
Review
2005
Peptide deformylase (PDF) is a prokaryotic metalloenzyme that is essential for bacterial growth but is not required by mammalian… (More)
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2004
2004
OBJECTIVES BB-83698 is a peptide deformylase inhibitor currently in clinical trials in Europe. The purpose of this study was to… (More)
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2004
2004
The efficacy of BB-83698, a novel potent peptide deformylase inhibitor, was evaluated in a mouse model of acute pneumonia. The… (More)
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2004
2004
BB-83698, a potent and selective inhibitor of peptide deformylase, was the first compound of this novel antibacterial class to… (More)
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2002
2002
The activities of six peptide deformylase (PDF) inhibitors against 107 respiratory tract pathogens were studied and compared to… (More)
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Review
2002
Review
2002
Peptide deformylase (PDF) represents one of the most exciting new targets for the development of novel antimicrobial… (More)
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