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BB-83698

National Institutes of Health

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Broader (1)

Hydroxamic Acids

Papers overview

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2017
2017
Computational Approaches to Identify a Derivative of Galardin as an Inhibitor of Mycobacterial Peptide Deformylase
Abstract. The metalloenzyme peptide deformylase (PDF) catalyzes the elimination of the N-formyl group from N-terminal methionine… 
2008
2008
Prediction of the binding modes between BB-83698 and peptide deformylase from Bacillus stearothermophilus by docking and molecular dynamics simulation.
2006
2006
Synthesis and Biological Evaluation of N-Formyl Hydroxylamine Derivatives as Potent Peptide Deformylase Inhibitors
Antibacterial resistance to hospital-acquired Grampositive bacterial pathogens, including methicillin-resistant Staphylococcus… 
Highly Cited
2004
Highly Cited
2004
In vitro antibacterial activity of the peptide deformylase inhibitor BB-83698.
OBJECTIVES BB-83698 is a peptide deformylase inhibitor currently in clinical trials in Europe. The purpose of this study was to… 
2004
2004
BB-3497, a peptide deformylase inhibitor, is active against Mycobacterium tuberculosis.
Sir, Bacterial peptide deformylase (PDF) belongs to a subfamily of metalloproteases catalysing the removal of the N-terminal… 
Highly Cited
2004
Highly Cited
2004
Pharmacokinetics in Animals and Humans of a First-in-Class Peptide Deformylase Inhibitor
ABSTRACT BB-83698, a potent and selective inhibitor of peptide deformylase, was the first compound of this novel antibacterial… 
2003
2003
Pneumococcal Pneumonia Deformylase Inhibitor , in a Mouse Model of Efficacy of BB-83698 , a Novel Peptide
2002
2002
In Vitro Activities of Peptide Deformylase Inhibitors against Gram-Positive Pathogens
ABSTRACT The activities of six peptide deformylase (PDF) inhibitors against 107 respiratory tract pathogens were studied and… 
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