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BAP1 gene

Known as: BRCA1 associated protein 1, BRCA1-ASSOCIATED PROTEIN 1, hucep-6 
This gene is involved in cellular growth regulation and is purported to have tumor suppression activity.
National Institutes of Health

Related topics

Related topics

8 relations
BAP1 Gene MutationBAP1 protein, humanCarcinoma of lungDeubiquitination

Papers overview

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Highly Cited
2018
Highly Cited
2018
Plasma Biomarkers of Brain Injury in Neonatal Hypoxic‐Ischemic Encephalopathy
Highly Cited
2017
Highly Cited
2017
Immunohistochemical detection of MTAP and BAP1 protein loss for mesothelioma diagnosis: Comparison with 9p21 FISH and BAP1 immunohistochemistry.
Highly Cited
2017
Highly Cited
2017
BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response
Significance BRCA1 associated protein 1 (BAP1) is a tumor suppressor and its inactivating mutations frequently occur in a subset… 
Highly Cited
2014
Highly Cited
2014
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.
Highly Cited
2011
Highly Cited
2011
Elevated serum ubiquitin carboxy-terminal hydrolase L1 is associated with abnormal blood-brain barrier function after traumatic brain injury.
Serum S100B elevations accurately reflect blood-brain barrier (BBB) damage. Because S100B is also present in peripheral tissues… 
Highly Cited
2004
Highly Cited
2004
UCHL1 is a Parkinson's disease susceptibility gene
An Erratum has been published for this article in Ann Neurol 2004;55:899. 
Highly Cited
2003
Highly Cited
2003
Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron.
Mammalian neuronal cells abundantly express a deubiquitylating enzyme, ubiquitin carboxy-terminal hydrolase 1 (UCH L1). Mutations… 
Highly Cited
2000
Highly Cited
2000
A new link between pesticides and Parkinson's disease
Environmental factors are thought to be an important cause of Parkinson's disease. A new study shows that rats chronically… 
Highly Cited
1999
Highly Cited
1999
Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson’s disease
Article abstract We investigated the association of PD with a recently reported I93M mutation of the ubiquitin carboxy-terminal… 
Highly Cited
1998
Highly Cited
1998
The ubiquitin pathway in Parkinson's disease
Mutations of the α-synuclein gene, have been identified in some familial forms of Parkinson's disease, and α-synuclein protein… 
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