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B cell selection

Known as: B lymphocyte selection, B-cell selection, B-lymphocyte selection 
The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

b cell differentiation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting.
Antigen-dependent engagement of germinal center (GC) B cell receptors (BCRs) promotes antigen internalization and presentation… Expand
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2016
2016
Antigen-affinity controls pre-germinal centser B cell selection by promoting Mcl-1 induction through BAFF receptor signaling
Upon antigen encounter, the responsive B cell pool undergoes stringent selection which eliminates cells with low B cell receptor… Expand
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2007
2007
Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation
Antigen receptor–mediated production of inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) in lymphocytes triggers the release of Ca2… Expand
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Review
2007
Review
2007
Complement receptor 2, natural antibodies and innate immunity: Inter-relationships in B cell selection and activation.
Complement receptor type 2 (CR2) is a receptor that serves as an important interface between the complement system and adaptive… Expand
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2003
2003
Human IgG1/IgG3 cryoglobulin suggesting lack of allelic exclusion.
Immunoglobulins undergoing cold-dependent precipitation are known as cryoglobulins. A type I cryoglobulin after Brouet et al… Expand
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2002
2002
Curtailing BCR signaling
The B-cell antigen receptor (BCR) is essential for B-cell selection, expansion, differentiation, and antigen presentation. The… Expand
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Highly Cited
2002
Highly Cited
2002
Role of BCR affinity in T cell–dependent antibody responses in vivo
Antibody affinity for antigen is believed to govern B lymphocyte selection during T-dependent immune responses. To examine… Expand
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Review
2000
Review
2000
B-cell antigen receptor competence regulates B-lymphocyte selection and survival.
Experimental evidence contradicts the simplistic view that during development all B cells expressing non autoreactive antigen… Expand
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Review
1997
Review
1997
Sites of B Lymphocyte Selection, Activation, and Tolerance in Spleen
  • Yong-Jun Liu
  • The Journal of experimental medicine
  • 1997
    • Corpus ID: 26754995
The immune system appears to be rigid, restricting one lymphocyte to make one antibody (([1][1])) and the peripheral B cell pool… Expand
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Review
1994
Review
1994
Molecular mechanisms for B lymphocyte selection: induction and regulation of antigen-receptor-mediated apoptosis of mature B cells in normal mice and their defect in autoimmunity-prone mice.
Apoptosis (programmed cell death) has been suggested to be involved in clonal elimination of self-reactive lymphocytes for the… Expand
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