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B-Cell Lymphoma 6 Protein

Known as: B Cell Lymphoma 6 Protein, c bcl 6 Protein, Cys-His2 Zinc Finger Transcription Factor 
A DNA-binding protein that contains an N-terminal BTB (POZ) DOMAIN and C-terminal CYS2-HIS2 ZINC FINGERS. It represses GENETIC TRANSCRIPTION of… 
National Institutes of Health

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Related topics

26 relations
ApoptosisBCL5 geneBCL6 geneBCL6 wt Allele

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Bcl6 protein, mouse

Papers overview

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Highly Cited
2010
Highly Cited
2010
Endothelial cells are activated during hypoxia via endoglin/ALK-1/SMAD1/5 signaling in vivo and in vitro.
2008
2008
PKR Regulates B56α-mediated BCL2 Phosphatase Activity in Acute Lymphoblastic Leukemia-derived REH Cells*
Protein phosphatase 2A (PP2A) is a heterotrimer comprising catalytic, scaffold, and regulatory (B) subunits. There are at least… 
Review
2003
Review
2003
Ambivalent role of BCL6 in cell survival and transformation
The BCL6 gene is often structurally altered and probably ‘misregulated’ in two different types of human B-cell non-Hodgkin… 
Review
2003
Review
2003
Analysis of CD10+ hairy cell leukemia.
Hairy cell leukemia (HCL) has been reported to sometimes express CD10. However, the reported frequencies have been quite variable… 
Highly Cited
2002
Highly Cited
2002
Follicular lymphoma without t(14;18) and with BCL-6 rearrangement: a lymphoma subtype with distinct pathological, molecular and clinical characteristics
Translocations involving the BCL-6 gene are frequently observed in diffuse large B cell lymphoma, but have rarely been reported… 
Highly Cited
2000
Highly Cited
2000
De novo acute B cell leukemia/lymphoma with t(14;18)
The t(14;18)(q32;q21) translocation is the most common translocation in B cell malignancies being found in 80% of follicular… 
Highly Cited
1999
Highly Cited
1999
Molecular pathogenesis of B cell malignancy: the role of BCL-6.
Human malignancies displaying a mature B cell phenotype include non-Hodgkin lymphoma, (NHL), chronic lymphocytic leukemia (CLL… 
Highly Cited
1998
Highly Cited
1998
Heterologous promoters fused to BCL6 by chromosomal translocations affecting band 3q27 cause its deregulated expression during B-cell differentiation.
The BCL6 gene encodes a POZ/Zinc-finger protein, which acts as a sequence-specific transcriptional repressor. It is expressed in… 
Highly Cited
1997
Highly Cited
1997
A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin's lymphoma results in replacement of the 5' regulatory region of BCL6 with a novel H4 histone gene.
3q27 translocations affecting the BCL6 gene can involve not only immunoglobulin genes (IG) but also other as yet uncharacterized… 
Highly Cited
1995
Highly Cited
1995
TTF, a gene encoding a novel small G protein, fuses to the lymphoma-associated LAZ3 gene by t(3;4) chromosomal translocation.
We have previously shown that the LAZ3/BCL6 gene encoding a potential transcription factor, is disrupted in B-diffuse large cell… 
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