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B-Cell Lymphoma 6 Protein

Known as: B Cell Lymphoma 6 Protein, c bcl 6 Protein, Cys-His2 Zinc Finger Transcription Factor 
A DNA-binding protein that contains an N-terminal BTB (POZ) DOMAIN and C-terminal CYS2-HIS2 ZINC FINGERS. It represses GENETIC TRANSCRIPTION of… Expand
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Follicular helper T (Tfh) cells provide selection signals to germinal center B cells, which is essential for long-lived antibody… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Several gene-expression signatures can be used to predict the prognosis in diffuse large-B-cell lymphoma, but the lack… Expand
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Highly Cited
2004
Highly Cited
2004
The human proto-oncogene BCL6 encodes a BTB/POZ-zinc-finger transcriptional repressor that is necessary for germinal-centre… Expand
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Review
2000
Review
2000
Overexpression of Bcl-2 can promote cancer or autoimmunity and affect sensitivity of tumor cells to chemotherapeutic drugs… Expand
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Highly Cited
2000
Highly Cited
2000
BCL-6, a transcriptional repressor frequently translocated in lymphomas, regulates germinal center B cell differentiation and… Expand
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Highly Cited
1999
Highly Cited
1999
Activation of CD40 is essential for thymus-dependent humoral immune responses and rescuing B cells from apoptosis. Many of the… Expand
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Highly Cited
1998
Highly Cited
1998
Diffuse large B-cell lymphoma (DLCL) is characterized by a marked degree of morphologic and clinical heterogeneity. We studied… Expand
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Highly Cited
1997
Highly Cited
1997
The gene encoding the BCL-6 transcriptional repressor is frequently translocated and mutated in diffuse large cell lymphoma. Mice… Expand
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Highly Cited
1997
Highly Cited
1997
Structural alterations of the promoter region of the BCL-6 proto-oncogene represent the most frequent genetic alteration… Expand
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Highly Cited
1995
Highly Cited
1995
Structural alterations of the 5' noncoding region of the BCL-6 gene have been found in 40% of diffuse large cell lymphoma (DLCL… Expand
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