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B-Cell Lymphoma 6 Protein

Known as: B Cell Lymphoma 6 Protein, c bcl 6 Protein, Cys-His2 Zinc Finger Transcription Factor 
A DNA-binding protein that contains an N-terminal BTB (POZ) DOMAIN and C-terminal CYS2-HIS2 ZINC FINGERS. It represses GENETIC TRANSCRIPTION of… 
National Institutes of Health

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26 relations
ApoptosisBCL5 geneBCL6 geneBCL6 wt Allele

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Bcl6 protein, mouse

Papers overview

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2014
2014
The Ansamycin Antibiotic, Rifamycin SV, Inhibits BCL6 Transcriptional Repression and Forms a Complex with the BCL6-BTB/POZ Domain
BCL6 is a transcriptional repressor that is over-expressed due to chromosomal translocations, or other abnormalities, in ∼40% of… 
2011
2011
Expression of follicular helper T cell markers in nodal peripheral T cell lymphomas: a tissue microarray analysis of 162 cases
Aims To evaluate the role of the follicular helper T (TFH) cell markers, CD10, BCL6, programmed death-1 (PD-1) and CXCL13, in the… 
2006
2006
A peptide aptamer to antagonize BCL-6 function
BCL-6 is a transcription factor essential for germinal centre B-cell development. The BCL-6 gene is involved in diffuse large… 
Review
2003
Review
2003
Ambivalent role of BCL6 in cell survival and transformation
The BCL6 gene is often structurally altered and probably ‘misregulated’ in two different types of human B-cell non-Hodgkin… 
2003
2003
Kinetics and STAT4‐ or STAT6‐mediated regulation of genes involved in lymphocyte polarization to Th1 and Th2 cells
Many genes implicated in Th1 and Th2 differentiation have been identified in both human and mouse. However, the functional roles… 
2003
2003
Prognostic value of bcl‐6, CD10 and CD38 immunoreactivity in stage I–II gastric lymphomas: Identification of a subset of CD10+ large B‐cell lymphomas with a favorable outcome
bcl‐6, CD10 and CD38 are useful markers for identifying 2 molecularly and prognostically distinct profiles of diffuse large B… 
2001
2001
Splicing factor SRP20 is a novel partner of BCL6 in a t(3;6)(q27;p21) translocation in transformed follicular lymphoma
The BCL6 gene mapped at chromosome band 3q27 encodes a zinc‐finger transcription factor and is frequently rearranged and… 
Highly Cited
1998
Highly Cited
1998
Clinical Relevance of BCL 2 , BCL 6 , and MYC Rearrangements in Diffuse Large B-Cell Lymphoma
Diffuse large B-cell lymphoma (DLCL) is characterized by a marked degree of morphologic and clinical heterogeneity. We studied… 
Highly Cited
1997
Highly Cited
1997
A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin's lymphoma results in replacement of the 5' regulatory region of BCL6 with a novel H4 histone gene.
3q27 translocations affecting the BCL6 gene can involve not only immunoglobulin genes (IG) but also other as yet uncharacterized… 
1994
1994
Heterogeneity in B‐Cell Neoplasms Associated with Rearrangement of the LAZ3 Gene on Chromosome Band 3q27
The LAZ3 gene has been identified on chromosome band 3q27, which is the breakpoint of reciprocal chromosome translocations… 
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