FAQ

Axotomy

Known as: Axotomies 
Transection or severing of an axon. This type of denervation is used often in experimental studies on neuronal physiology and neuronal death or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
05010015019542016

Related topics

Related topics

8 relations
AxonDenervationEducational aspectsMuscle denervation procedure
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Axotomy
Axon
Denervation
nursing therapy
Muscle denervation procedure
standards characteristics

Papers overview

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Highly Cited
2004
Highly Cited
2004
Neurosurgery: functional regeneration after laser axotomy.
Understanding how nerves regenerate is an important step towards developing treatments for human neurological disease, but… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain.
Phenotypic modification of dorsal root ganglion (DRG) neurons represents an important mechanism underlying neuropathic pain… (More)
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Highly Cited
2000
Highly Cited
2000
Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury.
Activating transcription factor 3 (ATF3), a member of ATF/CREB family of transcription factors, is induced in a variety of… (More)
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Highly Cited
1999
Highly Cited
1999
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
Autoimmunity to antigens of the central nervous system is usually considered detrimental. T cells specific to a central nervous… (More)
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Highly Cited
1997
Highly Cited
1997
BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration.
Rubrospinal neurons (RSNs) undergo a marked atrophy in the second week after cervical axotomy. This delayed atrophy is… (More)
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Highly Cited
1996
Highly Cited
1996
Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study.
PURPOSE To investigate in vivo the survival of retinal ganglion cells (RGC) 4 to 14 days after optic nerve (ON) transection alone… (More)
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Highly Cited
1995
Highly Cited
1995
Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.
PURPOSE To investigate whether retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis… (More)
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Highly Cited
1995
Highly Cited
1995
Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels.
We examined the role of extracellular calcium entry, the possible involvement of axonal calcium channels, and the potential… (More)
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Highly Cited
1995
Highly Cited
1995
Contributing factors to poor functional recovery after delayed nerve repair: prolonged axotomy.
The contribution of prolonged motoneuron axotomy to the poor functional recovery after delayed nerve repair was determined by… (More)
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Highly Cited
1994
Highly Cited
1994
Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.
Using quantitative anatomical techniques, we show that after intraorbital optic nerve transection in adult rats, virtually all… (More)
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