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Axotomy

Known as: Axotomies 
Transection or severing of an axon. This type of denervation is used often in experimental studies on neuronal physiology and neuronal death or… 
National Institutes of Health

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AxonDenervationEducational aspectsMuscle denervation procedure

Papers overview

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2007
2007
Acutely dissociated sensory neurons: normal or neuropathic? Focus on: "Dissociation of dorsal root ganglion neurons induces hyperexcitability that is maintained by increased responsiveness to cAMP…
The cell body of the primary nociceptive neuron, located in a ganglion, has an axon that bifurcates, one branch extending to the… 
2005
2005
Temporal changes in catecholamine synthesis of rat forebrain structures after axotomy
Axotomy was performed by means of a complete transverse cerebral hemisection in rats at the level of the caudal hypothalamus. An… 
Review
2004
Review
2004
A quantitative study of subsurface cisterns and their relationships in normal and axotomized hypoglossal neurones
SummaryA quantitative ultrastructural survey was made of subsurface cisterns and their association with overlying structures in… 
2001
2001
Bcl-2 is not required in retinal ganglion cells surviving optic nerve axotomy
Axotomy of the optic nerve in rodents induces the majority of retinal ganglion cells (RGCs) to undergo apoptosis: Only 10–15… 
1995
1995
Deletion of 3′-Untranslated Region Alters the Level of mRNA Expression of a Neurofilament Light Subunit Transgene (*)
High levels of neurofilament (NF) mRNA expression are attained during early postnatal development and are a major determinant of… 
1986
1986
Altered excitability of goldfish mauthner cell following axotomy. I. Characterization and correlations with somatic and axonal morphological reactions.
Axonal transection 7-10 mm distal to the cell body of the goldfish Mauthner (M) cell induced alterations in its excitability… 
1986
1986
The effect of axotomy on posttetanic potentiation of group Ia synapses in the cat.
Posttetanic potentiation (PTP) of composite Ia excitatory postsynaptic potentials (EPSPs) has been studied in normal cat alpha… 
1981
1981
Ionic and metabolic dependence of axotomy‐induced somatic membrane changes in crayfish.
1. Axotomy induces a transient change in the soma membrane from non‐spiking to spiking in many neurones of the crayfish abdominal… 
1973
1973
QUANTITATIVE MICROFLUORIMETRIC AND NEUROCHEMICAL STUDIES ON DEGENERATING ADRENERGIC NERVES
The short term effects on noradrenaline (NA) uptake-storage mechanisms and nerve density of the adrenergic nerves in mouse and… 
1955
1955
The temporal course of the effects of postganglionic axotomy on the inferior mesenteric ganglion of the cat
Some years ago it was observed (Acheson, Lee & Morison, 1942) that cutting the phrenic nerve caused, over a period of 3 weeks, a… 
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