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Axotomy
Known as:
Axotomies
Transection or severing of an axon. This type of denervation is used often in experimental studies on neuronal physiology and neuronal death or…
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1954-2017
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1954
2016
Related topics
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8 relations
Axon
Denervation
Educational aspects
Muscle denervation procedure
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Related mentions per year
Related mentions per year
1936-2018
1940
1960
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2000
2020
Axotomy
Axon
Denervation
nursing therapy
Muscle denervation procedure
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Neurosurgery: functional regeneration after laser axotomy.
Mehmet Fatih Yanik
,
Hulusi Cinar
,
Hediye Nese Cinar
,
Andrew D. Chisholm
,
Yishi Jin
,
Adela Ben-Yakar
Nature
2004
Understanding how nerves regenerate is an important step towards developing treatments for human neurological disease, but…
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Highly Cited
2002
Highly Cited
2002
Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain.
Hua-sheng Xiao
,
Qiuhua Huang
,
+14 authors
Xu Zhang
Proceedings of the National Academy of Sciences…
2002
Phenotypic modification of dorsal root ganglion (DRG) neurons represents an important mechanism underlying neuropathic pain…
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Highly Cited
2000
Highly Cited
2000
Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury.
Hanako Tsujino
,
Eisaku Kondo
,
+6 authors
Kyo Noguchi
Molecular and cellular neurosciences
2000
Activating transcription factor 3 (ATF3), a member of ATF/CREB family of transcription factors, is induced in a variety of…
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Highly Cited
1999
Highly Cited
1999
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
Gila Moalem
,
Raya Leibowitz–Amit
,
Eti Yoles
,
Felix Mor
,
Irun R. Cohen
,
Michal Schwartz
Nature Medicine
1999
Autoimmunity to antigens of the central nervous system is usually considered detrimental. T cells specific to a central nervous…
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Highly Cited
1997
Highly Cited
1997
BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration.
Naoto Kobayashi
,
Dorothy Shu-Ping Fan
,
Klaus M. Giehl
,
Andréanne Bédard
,
Sandra Wiegand
,
Walter F Tetzlaff
The Journal of neuroscience : the official…
1997
Rubrospinal neurons (RSNs) undergo a marked atrophy in the second week after cervical axotomy. This delayed atrophy is…
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Highly Cited
1996
Highly Cited
1996
Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study.
P Peinado-Ramón
,
Maria João Salvador
,
María Paz Villegas-Pérez
,
Manuel Vidal-Sanz
Investigative ophthalmology & visual science
1996
PURPOSE To investigate in vivo the survival of retinal ganglion cells (RGC) 4 to 14 days after optic nerve (ON) transection alone…
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Highly Cited
1995
Highly Cited
1995
Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.
Howard Quigley
,
Robert W Nickells
,
Larisa A. Kerrigan
,
Matthew Pease
,
Danielle Thibault
,
Donald J. Zack
Investigative ophthalmology & visual science
1995
PURPOSE To investigate whether retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis…
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Highly Cited
1995
Highly Cited
1995
Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels.
Edith George
,
Jonathan D. Glass
,
J. W. Griffin
The Journal of neuroscience : the official…
1995
We examined the role of extracellular calcium entry, the possible involvement of axonal calcium channels, and the potential…
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Highly Cited
1995
Highly Cited
1995
Contributing factors to poor functional recovery after delayed nerve repair: prolonged axotomy.
S. Y. Fu
,
T. R. Gordon
The Journal of neuroscience : the official…
1995
The contribution of prolonged motoneuron axotomy to the poor functional recovery after delayed nerve repair was determined by…
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Highly Cited
1994
Highly Cited
1994
Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.
Majoska Berkelaar
,
David Clarke
,
Y. C. Wang
,
Gordon Bray
,
Álvaro Aguayo
The Journal of neuroscience : the official…
1994
Using quantitative anatomical techniques, we show that after intraorbital optic nerve transection in adult rats, virtually all…
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