Autophagosome

Known as: Autophagic Vacuole, Autophagic vacuoles, Autophagosomes 
Large spherical double-layered structures which function in AUTOPHAGY to engulf intracellular components such as ORGANELLES or pathogens. Their outer… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Macroautophagy, or simply autophagy, is a degradative pathway that delivers cytoplasmic components, including cytosol and… (More)
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Review
2013
Review
2013
Healthy cells use autophagy as a general 'housekeeping' mechanism and to survive stress, including stress induced by nutrient… (More)
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Highly Cited
2013
Highly Cited
2013
Autophagy is a tightly regulated intracellular bulk degradation/recycling system that has fundamental roles in cellular… (More)
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Highly Cited
2010
Highly Cited
2010
Starvation-induced autophagosomes engulf cytosol and/or organelles and deliver them to lysosomes for degradation, thereby… (More)
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Highly Cited
2010
Highly Cited
2010
Autophagy is primarily considered a non-selective degradation process induced by starvation. Nutrient-independent basal autophagy… (More)
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Highly Cited
2008
Highly Cited
2008
Macroautophagy, a major pathway for organelle and protein turnover, has been implicated in the neurodegeneration of Alzheimer's… (More)
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Review
2007
Review
2007
Eukaryotic cells employ autophagy to degrade damaged or obsolete organelles and proteins. Central to this process is the… (More)
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Highly Cited
2007
Highly Cited
2007
During the process of autophagy, autophagosomes undergo a maturation process consisting of multiple fusions with endosomes and… (More)
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Highly Cited
2003
Highly Cited
2003
Macroautophagy mediates the bulk degradation of cytoplasmic components. It accounts for the degradation of most long-lived… (More)
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Highly Cited
1998
Highly Cited
1998
We studied the effects of bafilomycin A1, a potent and specific inhibitor of vacuolar H+ ATPase (V-ATPase), on the process of… (More)
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