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Autophagosome

Known as: Autophagic Vacuole, Autophagic vacuoles, Autophagosomes 
Large spherical double-layered structures which function in AUTOPHAGY to engulf intracellular components such as ORGANELLES or pathogens. Their outer… 
National Institutes of Health

Related topics

Related topics

15 relations
ATG16L1 protein, humanAtg7 protein, humanAutophagyCytoplasm

Broader (1)

Vacuole

Narrower (1)

autophagosome membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17
Autophagosome–lysosome fusion requires the autophagosomal SNARE syntaxin 17. Syntaxin 17 interacts with the HOPS-tethering… 
Review
2010
Review
2010
Autophagosome formation in mammalian cells
Autophagy is a fundamental intracellular trafficking pathway conserved from yeast to mammals. It is generally thought to play a… 
Highly Cited
2007
Highly Cited
2007
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.
Highly Cited
2007
Highly Cited
2007
LC3, an Autophagosome Marker, Can be Incorporated into Protein Aggregates Independent of Autophagy: Caution in the Interpretation of LC3 Localization
Autophagy is an intracellular bulk degradation system, through which a portion of the cytoplasm is delivered to lysosomes to be… 
Review
2007
Review
2007
ROS, mitochondria and the regulation of autophagy.
Review
2005
Review
2005
Autophagy: molecular machinery for self-eating
Autophagy is a highly conserved process in eukaryotes in which the cytoplasm, including excess or aberrant organelles, is… 
Highly Cited
2001
Highly Cited
2001
A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation.
Autophagy is a normal degradative pathway that involves the sequestration of cytoplasmic portions and intracellular organelles in… 
Highly Cited
1998
Highly Cited
1998
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells.
We studied the effects of bafilomycin A1, a potent and specific inhibitor of vacuolar H+ ATPase (V-ATPase), on the process of… 
Highly Cited
1995
Highly Cited
1995
Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis
The CA1 pyramidal neurons in the hippocampus are selectively vulnerable to transient ischemic damage. In experimental animals… 
Highly Cited
1966
Highly Cited
1966
LYSOSOME FUNCTION IN THE REGULATION OF THE SECRETORY PROCESS IN CELLS OF THE ANTERIOR PITUITARY GLAND
The nature and content of lytic bodies and the localization of acid phosphatase (AcPase) activity were investigated in… 
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