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Aurothiomalate

National Institutes of Health

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Gold Sodium ThiomalateMyochrysine
Poisoning by antirheumatics [antiphlogistics]

Papers overview

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Highly Cited
2008
Highly Cited
2008
Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells.
The antirheumatoid agent aurothiomalate (ATM) is a potent inhibitor of oncogenic PKC iota. ATM inhibits non-small lung cancer… 
Highly Cited
2008
Highly Cited
2008
Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells.
Highly Cited
2006
Highly Cited
2006
Aurothiomalate Inhibits Transformed Growth by Targeting the PB1 Domain of Protein Kinase Cι*
We recently identified the gold compound aurothiomalate (ATM) as a potent inhibitor of the Phox and Bem1p (PB1)-PB1 domain… 
Highly Cited
2006
Highly Cited
2006
Gold nanocluster formation using metallothionein: mass spectrometry and electron microscopy.
Highly Cited
2004
Highly Cited
2004
Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c.
Review
1997
Review
1997
The mechanisms of action of disease-modifying antirheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines.
Highly Cited
1983
Highly Cited
1983
Consumption coagulopathy associated with systemic juvenile rheumatoid arthritis.
Highly Cited
1981
Highly Cited
1981
Localization of gold in biological tissue
SummaryA detailed description is given of a method by which gold can be visualized in frozen, paraffin and Epon sections… 
1977
1977
Determination of gold in plasma and plasma fractions by atomic absorption spectrometry and by neutron activation analysis.
Highly Cited
1974
Highly Cited
1974
Pharmacodynamics of 197Au and 195Au labeled aurothiomalate in blood. Correlation with course of rheumatoid arthritis, gold toxicity and gold excretion.
The relationships between serum stable gold (197Au) concentration and serum and whole blood radioactive gold (195Au… 
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