J. Bondeson

Publications70
h-index16
Citations693
Highly Influential Citations24
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The mechanisms of action of disease-modifying antirheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines.
1. Rheumatoid arthritis (RA) is probably the most common source of treatable disability. A major problem in modern rheumatology is that the mechanism(s) of action of the currently used… Expand
  • 117
  • 7
The Biddenden Maids: a curious chapter in the history of conjoined twins.
  • J. Bondeson
  • Medicine
  • Journal of the Royal Society of Medicine
  • 1 April 1992
  • 43
  • 3
Buried Alive: The Terrifying History of Our Most Primal Fear
Readers of Edgar Allan Poe's tales-just think of The Premature Burial-may comfort themselves with the notion that Poe must have exaggerated: surely people of the 1800s could not have been at risk of… Expand
  • 34
  • 2
Differential effects of tenidap on the zymosan- and lipopolysaccharide-induced expression of mRNA for proinflammatory cytokines in macrophages.
Tenidap is a novel antirheumatic drug that combines cyclooxygenase inhibition with cytokine modulating qualities. We demonstrate here that tenidap inhibits the zymosan-induced expression of both… Expand
  • 20
  • 1
Julia Pastrana, the nondescript: an example of congenital, generalized hypertrichosis terminalis with gingival hyperplasia.
Julia Pastrana (1834-1860) has gained immortality as one of the most extreme cases of generalized hypertrichosis upon record. When she was exhibited for money in the United States and Europe during… Expand
  • 33
  • 1
Caroline Crachami, the Sicilian Fairy: a case of bird-headed dwarfism.
  • J. Bondeson
  • History, Medicine
  • American journal of medical genetics
  • 15 September 1992
One of the most remarkable cases of extreme dwarfism on record is Caroline Crachami, the Sicilian Fairy. She was born in 1815, and was taken to London to be exhibited for money in 1824. Due to her… Expand
  • 12
  • 1
Effects of tenidap on intracellular signal transduction and the induction of proinflammatory cytokines: a review.
  • J. Bondeson
  • Medicine
  • General pharmacology
  • 1 September 1996
Tenidap is a novel, once-daily antirheumatic drug which has shown promising results against rheumatoid arthritis in extensive clinical trials. It combines NSAID-like cyclooxygenase inhibition with… Expand
  • 19
  • 1
Antimalarial drugs inhibit phospholipase A2 activation and induction of interleukin 1beta and tumor necrosis factor alpha in macrophages: implications for their mode of action in rheumatoid arthritis.
1. The effects of antimalarial drugs on the intracellular signaling leading to activation of the phospholipase C and phospholipase A2 pathways and the induction of proinflammatory cytokines have been… Expand
  • 56
  • 1
Antirheumatic gold compounds and penicillamine enhance protein kinase C‐mediated activation of the arachidonate‐ mobilizing phospholipase A2 in mouse macrophages
The effects of antirheumatic gold compounds and D‐penicillamine on protein kinase C‐ and Ca2+‐ mediated activation of arachidonate mobilization and the formation of eicosanoids in mouse macrophages… Expand
  • 14
  • 1
A cabinet of medical curiosities
In this book of amazing oddities, Jan Bondeson explores unexpected, gruesome, and bizarre aspects of the history of medicine. He regales us with stories of spontaneous human combustion; vicious… Expand
  • 31
  • 1