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Ataxins

Known as: Proteins, Spinocerebellar Ataxia, Ataxin Proteins, Spinocerebellar Ataxia Proteins 
A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in… Expand
National Institutes of Health

Papers overview

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2013
2013
Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins and the ataxin proteins are… Expand
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Review
2010
Review
2010
Huntington’s disease (HD) and spinocerebellar ataxias (SCAs) are autosomal-dominant neurodegenerative disorders. HD is caused by… Expand
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Review
2010
Review
2010
  • J. S. Jiménez
  • Journal of Alzheimer's disease : JAD
  • 2010
  • Corpus ID: 8922643
A number of neurodegenerative diseases, including Alzheimer's disease, tauopathies, Parkinson's disease, and synucleinopathies… Expand
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Highly Cited
2009
Highly Cited
2009
Amyloid fibrils are long, helically symmetric protein aggregates that can display substantial variation (polymorphism), including… Expand
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Highly Cited
2008
Highly Cited
2008
In this work we investigate subcellular localization and proteolytic cleavage of different forms of ataxin-3 (AT-3), the protein… Expand
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2007
2007
Abstract The neurodegenerative disease spinocerebellar ataxia type 3 (SCA3) is caused by the presence of an extended… Expand
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2007
2007
The authors studied inclusion formation in vitro using transiently transfected PC12 cells, with epitope-tagged and untagged full… Expand
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Highly Cited
2003
Highly Cited
2003
The spinocerebellar ataxias (SCAs) are a class of hereditary neurodegenerative diseases, which are caused by the pathological… Expand
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2003
2003
The deposition of abnormal protein fibrils is a prominent pathological feature of many different ‘protein conformational… Expand
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1995
1995
  • R. Rosenberg
  • The New England journal of medicine
  • 1995
  • Corpus ID: 41455215
Neurology textbooks are replete with descriptions of clinical syndromes of ataxia due to various forms of spinocerebellar… Expand
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