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Arbaclofen

Known as: Baclofen R-, d-Baclofen, (R)-(-)-Baclofen 
 
National Institutes of Health

Papers overview

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2017
2017
Several lines of emerging data point to an imbalance between neuronal excitation and inhibition in at least a subgroup of… Expand
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2017
2017
Abstract Fragile X syndrome is a genetic condition resulting from FMR1 gene mutation that leads to intellectual disability… Expand
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Highly Cited
2016
Highly Cited
2016
BackgroundArbaclofen improved multiple abnormal phenotypes in animal models of fragile X syndrome (FXS) and showed promising… Expand
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Review
2015
Review
2015
AbstractAutism spectrum disorders (ASDs) are a group of neurodevelopmental disorders including autistic disorder, Asperger… Expand
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Highly Cited
2014
Highly Cited
2014
STX209 (arbaclofen), a selective GABA-B agonist, is hypothesized to modulate the balance of excitatory to inhibitory… Expand
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Review
2014
Review
2014
Current therapeutics in autism spectrum disorders (ASD) only treat the associated symptoms, without addressing core social… Expand
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Highly Cited
2012
Highly Cited
2012
Administration of a selective GABAB agonist to individuals with fragile X syndrome improves their deficits in social avoidance, a… Expand
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Highly Cited
2012
Highly Cited
2012
Pharmacological activation of the GABAB receptor with arbaclofen in a mouse model of fragile X syndrome corrects neuronal defects… Expand
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2012
2012
Autism is a neurodevelopmental disorder consisting of a constellation of symptoms that sometimes occur as part of a complex… Expand
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Review
2011
Review
2011
STX209 (arbaclofen) is a γ-amino butyric acid type B (GABA(B)) receptor agonist from Seaside Therapeutics currently in clinical… Expand
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