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Arbaclofen

Known as: Baclofen R-, d-Baclofen, (R)-(-)-Baclofen 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Fragile X syndrome (FXS) is a common monogenetic cause of intellectual disability, autism spectrum features, and a broad range of… Expand
Highly Cited
2017
Highly Cited
2017
Several lines of emerging data point to an imbalance between neuronal excitation and inhibition in at least a subgroup of… Expand
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2017
2017
Abstract Fragile X syndrome is a genetic condition resulting from FMR1 gene mutation that leads to intellectual disability… Expand
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Highly Cited
2016
Highly Cited
2016
BackgroundArbaclofen improved multiple abnormal phenotypes in animal models of fragile X syndrome (FXS) and showed promising… Expand
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Highly Cited
2014
Highly Cited
2014
STX209 (arbaclofen), a selective GABA-B agonist, is hypothesized to modulate the balance of excitatory to inhibitory… Expand
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Review
2014
Review
2014
  • R. Frye
  • Drug, healthcare and patient safety
  • 2014
  • Corpus ID: 15287818
Autism spectrum disorder (ASD) is a behaviorally defined disorder which has increased in prevalence over the last two decades… Expand
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Review
2013
Review
2013
RationaleAdvances in understanding the underlying mechanisms of conditions such as fragile X syndrome (FXS) and autism spectrum… Expand
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Highly Cited
2012
Highly Cited
2012
Administration of a selective GABAB agonist to individuals with fragile X syndrome improves their deficits in social avoidance, a… Expand
Highly Cited
2012
Highly Cited
2012
Pharmacological activation of the GABAB receptor with arbaclofen in a mouse model of fragile X syndrome corrects neuronal defects… Expand
2012
2012
Autism is a neurodevelopmental disorder consisting of a constellation of symptoms that sometimes occur as part of a complex… Expand