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Aptamers, Peptide

Known as: Aptamers, Peptide [Chemical/Ingredient], Peptide Aptamers 
Peptide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

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TRIPalpha protein, S cerevisiae

Papers overview

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2018
2018
In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer
Targeted nanomedicines offer many advantages over macromolecular therapeutics that rely only on passive accumulation within the… 
2014
2014
Functional isoDNA aptamers: modified thrombin binding aptamers with a 2'-5'-linked sugar-phosphate backbone (isoTBA).
The regioisomeric 3'-deoxy-2'-5'-linked thrombin binding DNA aptamers (isoTBAs) were chemically synthesized and their ability to… 
2013
2013
An affinity capture involved enzymatic assay for thrombin by using peptide aptamers as affinity ligands on magnetic beads.
Here we present a sensitive and specific assay for thrombin through the affinity capture of thrombin with mRNA display generated… 
Review
2013
Review
2013
Recent advancements in small molecule inhibitors of insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase as anticancer agents.
Advancements in understanding of the genetics, genomics, biochemistry and the pharmacology of cancer inhuman, have driven the… 
Highly Cited
2007
Highly Cited
2007
Peptide aptamers in label-free protein detection: 1. Characterization of the immobilized scaffold.
Protein microarray development is absolutely dependent upon the ability to construct interfaces capable of specific, stable… 
2007
2007
Microarray-formatted clinical biomarker assay development using peptide aptamers to anterior gradient-2.
Anterior gradient-2 protein was identified using proteomic technologies as a p53 inhibitor which is overexpressed in human… 
2007
2007
Modulation of Nr-13 antideath activity by peptide aptamers
Tumor cells are characterized by deregulated proliferation and resistance to proapoptotic stimuli. The Bcl-2 family of… 
2006
2006
p53-dependent inhibition of mammalian cell survival by a genetically selected peptide aptamer that targets the regulatory subunit of protein kinase CK2
Based on the perturbation of its expression in human cancers and on its involvement in transformation and tumorigenesis, protein… 
2001
2001
Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV‐16 E7 oncoprotein
Human papillomaviruses (HPV) of the high‐risk type are causally involved in human tumors, in particular cervical carcinoma… 
2000
2000
Selection of genetic agents from random peptide aptamer expression libraries.
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