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Apicoplasts

Known as: Apicomplexan Plastid, Apicoplast, Plastids, Apicomplexan 
Non-photosynthetic plastids derived from RED ALGAE endosymbionts. They are found in species of the phylum APICOMPLEXA including PLASMODIUM MALARAIAE.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The only essential function of a unique plastid organelle, the apicoplast, in blood-stage P. falciparum is the production of… Expand
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Highly Cited
2007
Highly Cited
2007
ABSTRACT Several classes of antibiotics exert antimalarial activity. The mechanisms of action of antibiotics against malaria… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Tetracyclines are effective but slow-acting antimalarial drugs whose mechanism of action remains uncertain. To… Expand
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Highly Cited
2005
Highly Cited
2005
Plasmodium parasites are unicellular eukaryotes that undergo a series of remarkable morphological transformations during the… Expand
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Review
2004
Review
2004
Discovery of a relict chloroplast (the apicoplast) in malarial parasites presented new opportunities for drug development. The… Expand
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Highly Cited
2004
Highly Cited
2004
The apicomplexan Cryptosporidium parvum is an intestinal parasite that affects healthy humans and animals, and causes an… Expand
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Highly Cited
2003
Highly Cited
2003
Transit peptides mediate protein targeting into plastids and are only poorly understood. We extracted amino acid features from… Expand
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Highly Cited
2002
Highly Cited
2002
The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of malaria, and kills more than one million… Expand
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Highly Cited
2001
Highly Cited
2001
The malaria causing protozoan Plasmodium falciparum contains a vestigal, non-photosynthetic plastid, the apicoplast. Numerous… Expand
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Highly Cited
1999
Highly Cited
1999
A mevalonate-independent pathway of isoprenoid biosynthesis present in Plasmodium falciparum was shown to represent an effective… Expand
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