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Apicoplasts

Known as: Apicomplexan Plastid, Apicoplast, Plastids, Apicomplexan 
Non-photosynthetic plastids derived from RED ALGAE endosymbionts. They are found in species of the phylum APICOMPLEXA including PLASMODIUM MALARAIAE.
National Institutes of Health

Related topics

Related topics

4 relations
MicrobiologicalProcess of secretionaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2011
Highly Cited
2011
Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum
The only essential function of a unique plastid organelle, the apicoplast, in blood-stage P. falciparum is the production of… 
Highly Cited
2008
Highly Cited
2008
Toxoplasma gondii Tic20 is essential for apicoplast protein import
Apicomplexan parasites harbor a secondary plastid that has lost the ability to photosynthesize yet is essential for the parasite… 
Highly Cited
2007
Highly Cited
2007
Multiple Antibiotics Exert Delayed Effects against the Plasmodium falciparum Apicoplast
ABSTRACT Several classes of antibiotics exert antimalarial activity. The mechanisms of action of antibiotics against malaria… 
Highly Cited
2006
Highly Cited
2006
Tetracyclines Specifically Target the Apicoplast of the Malaria Parasite Plasmodium falciparum
ABSTRACT Tetracyclines are effective but slow-acting antimalarial drugs whose mechanism of action remains uncertain. To… 
Highly Cited
2006
Highly Cited
2006
Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii
Apicomplexan parasites are the cause of numerous important human diseases including malaria and AIDS-associated opportunistic… 
Highly Cited
2005
Highly Cited
2005
Development of the endoplasmic reticulum, mitochondrion and apicoplast during the asexual life cycle of Plasmodium falciparum
Plasmodium parasites are unicellular eukaryotes that undergo a series of remarkable morphological transformations during the… 
Highly Cited
2004
Highly Cited
2004
Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method.
Review
2003
Review
2003
Plasmodium Biology Genomic Gleanings
Review
1999
Review
1999
Apicomplexan plastids as drug targets.
Highly Cited
1998
Highly Cited
1998
Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum.
A vestigial, nonphotosynthetic plastid has been identified recently in protozoan parasites of the phylum Apicomplexa. The… 
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