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Apical Ectodermal Ridge

A thickened surface layer of ectodermal cells found at the end of each limb bud in the developing embryo.
National Institutes of Health

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Related topics

1 relation
Limb Buds

Papers overview

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Review
2005
Review
2005
[Complex polydactyly of the limbs: mirror foot. Report of two cases and review of literature].
Polydactyly is the most common congenital limb anomaly occurring both as an isolated defect or as part of a syndrome. However… 
2004
2004
On the migration of epidermal melanoblasts in the avian embryonic wing bud
SummaryAfter heterotopic grafting of quail neural crest cells to the wing buds of embryos of an unpigmented chicken strain… 
2002
2002
10 Premature regression of the leg apical ectodermal ridge (AER) in the Japanese chick wingless mutant.
The autosomal dominant Japanese wingless mutant has varying degrees of wing and leg truncations. The wing phenotype is more… 
1984
1984
Orientated movement of myogenic cells in the avian limb bud and its dependence on presence of the apical ectodermal ridge.
1984
1984
Orientated movement of myogenic cells in the avian limb bud and its dependence on presence of the apical ectodermal ridge.
1981
1981
Pathogenesis of bromodeoxyuridine-induced polydactyly.
Intraperitoneal injection of BUdR on day 11 or 12 of rat gestation produced preaxial polydactyly of the hindlimb. The… 
1978
1978
Lack of correlation between mesenchymal cell death and morphogenesis after different extents of apical ectodermal ridge/rim ectoderm removal in the chick embryo wing bud.
The removal of the apical ectodermal ridge (A.E.R.) subsequently causes distal deletion defects in the limb. There have been… 
1977
1977
Reduction of the rate of outgrowth, cell density, and cell division following removal of the apical ectodermal ridge of the chick limb-bud.
Removal of the apical ectodermal ridge causes a reduction in the rate of outgrowth of the wing-bud and the loss of distal parts… 
1975
1975
The function of the ectodermal apical ridge and distinctive characteristics of adjacent distal mesoderm in the avian wing-bud.
Blocks of mesoderm about 0-1 mm in diameter were isolated from various regions of chick wing-buds of stages 17 through 22 and… 
1974
1974
Ultrastructural features of ectodermal--mesenchymal relationships in the developing limb of Xenopus laevis.
Electron microscopical study of the formation of the hind limb of the toad Xenopus laevis between stages 49 and 53 of larval…