Apical Ectodermal Ridge

A thickened surface layer of ectodermal cells found at the end of each limb bud in the developing embryo.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2018
0246819642018

Papers overview

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2011
2011
The apical ectodermal ridge (AER) is a specialized epithelium located at the distal edge of the limb bud that directs outgrowth… (More)
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2008
2008
The apical ectodermal ridge (AER) is a transient embryonic structure essential for the induction, patterning and outgrowth of the… (More)
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2003
2003
doubleridge is a transgene-induced mutation characterized by polydactyly and syndactyly of the forelimbs. The transgene insertion… (More)
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Highly Cited
2002
Highly Cited
2002
To determine the role of fibroblast growth factor (FGF) signalling from the apical ectodermal ridge (AER), we inactivated Fgf4… (More)
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Highly Cited
2001
Highly Cited
2001
We demonstrate that signaling via the bone morphogenetic protein receptor IA (BMPR-IA) is required to establish two of the three… (More)
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2001
2001
Dorsoventral (DV) patterning of the vertebrate limb requires the function of the transcription factor Engrailed 1 (EN1) in the… (More)
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Highly Cited
2000
Highly Cited
2000
Vertebrate limb development depends on signals from the apical ectodermal ridge (AER), which rims the distal tip of the limb bud… (More)
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Highly Cited
1999
Highly Cited
1999
The interactions between fibroblast growth factors (FGF) and their receptors have important roles in mediating mesenchymal… (More)
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Highly Cited
1998
Highly Cited
1998
Signals from the apical ectodermal ridge (AER) of the developing vertebrate limb, including fibroblast growth factor-8 (FGF-8… (More)
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1984
1984
Fragments of quail wing bud containing myogenic cells of somitic origin and fragments of quail sphlanchopleural tissue were… (More)
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