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Antisense Technology

The use of nucleic acid oligomers to bind to a specific mRNA to deter protein production.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
HIGH AFFINITY DNA BINDING COMPOUNDS AS ADJUVANTS IN ANTISENSE TECHNOLOGY
(54) HIGH AFFINITY DNA BINDING (56) References Cited COMPOUNDS AS ADJUVANTS IN PUBLICATIONS ANTISENSE TECHNOLOGY Johnson et al… 
2014
2014
Impairs Angiogenesis NEU 1 Sialidase Regulates the Sialylation State of CD 31 and Disrupts CD 31-Driven Capillary-Like Tube Formation in Human Lung Microvascular
The highly sialylated vascular endothelial surface undergoes changes in sialylation upon adopting the migratory/angiogenic… 
2013
2013
LIPID METABOLISM CORRECTION BY ANTISENSE TECHNOLOGY
Antisense oligonucleotides (ASO) technology in elaboration of drugs for lipid metabolism correction is discussed. The main ASO… 
2013
2013
Role of JNK Signalling and AHR in Fibrosis, Implications for New
In this study a role for signalling molecules in experimental fibrosis is established using a novel model of fibrosis. The yellow… 
Review
2003
Review
2003
The clinical progress of antisense technology in the treatment of cancer
According to the base complementation, the principle antisense technology is the sequence specific binding of complementary… 
Review
2002
Review
2002
Minireview Antisense Oligonucleotides : Basic Concepts and Mechanisms
Conceptual simplicity, the possibility of rational design, relatively inexpensive cost, and developments in the sequencing of… 
2002
2002
RATIONAL STATISTICAL DESIGN OF ANTISENSE OLIGONUCLEOTIDES FOR HIGH THROUGHPUT FUNCTIONAL GENOMICS AND DRUG TARGET VALIDATION
RNAs are versatile molecules that are involved in many important cellular activities including protein synthesis, antisense… 
Review
1997
Review
1997
Harnessing the power of antisense technology for combination chemotherapy.
The Bcr-abl fusion protein, which results when the abl (also known as ABL) proto-oncogene translocates from chromosome 9 to… 
1995
1995
Studies on the role ofc-fos in the mammalian brain: Application of antisense technology.
The studies in this thesis have examined the role of the immediate-early gene, c-fos, in brain function. The immediate-early… 
1994
1994
Modulation of plant gene expression using antisense technology and gene amplification: Alteration of shikimate pathway gene expression
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