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Antisense Technology

The use of nucleic acid oligomers to bind to a specific mRNA to deter protein production.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
LIPID METABOLISM CORRECTION BY ANTISENSE TECHNOLOGY
Antisense oligonucleotides (ASO) technology in elaboration of drugs for lipid metabolism correction is discussed. The main ASO… 
Review
2011
Review
2011
Making sense of therapeutics using antisense technology
Introduction: Antisense oligonucleotides (ASOs) are short synthetic single-stranded DNA sequences that bind to and induce the… 
Review
2010
Review
2010
siRNA: Sojourn from discovery to delivery challenges and clinics
Since the Nobel prize-winning discovery of RNA interference (RNAi) in 1998, considerable money has been invested in the… 
2010
2010
Bt brinjal splits Indian cabinet
volume 28 number 4 april 2010 nature biotechnology The news was not all positive, however. Elevated liver enzymes were observed… 
2008
2008
Evaluation of cystine transport in cultured human kidney cells and establishment of cystinuria type I phenotype by antisense technology
Cystinuria is a rare hereditary disease resulting in recurrent stone formation and the need for repeated invasive interventions… 
Review
2003
Review
2003
Antisense DNAs as targeted genetic medicine to treat cancer
Nucleic acid therapies represent a direct genetic approach for cancer treatment. Such an approach takes advantage of mechanisms… 
Review
2001
Review
2001
Redirection of drug metabolism using antisense technology.
The cytochrome P450 (CYP) family is the most catalytically versatile component of the phase I oxidation metabolic pathway and… 
2000
2000
Gene switching: analyzing a broad range of mutations using steric block antisense oligonucleotides.
Review
1999
Review
1999
Conformationally restricted carbohydrate-modified nucleic acids and antisense technology.
1997
1997
Antisense S-oligodeoxynucleotides down-regulate TGFbeta-production by Kupffer cells from CCl4-injured rat livers.
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