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Anti-TIM-3 Monoclonal Antibody MBG453
Known as:
Anti-TIM3 Checkpoint Inhibitor MBG453
, MBG 453
, MBG453
An inhibitor of the inhibitory T-cell receptor T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3; hepatitis A virus cellular…
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National Institutes of Health
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Related topics
Related topics
1 relation
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Phase Ib Study of the Anti-TIM-3 Antibody MBG453 in Combination with Decitabine in Patients with High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)
U. Borate
,
J. Esteve
,
+20 authors
A. Wei
Blood
2019
Corpus ID: 214266841
Co-senior authors Andrew Brunner and Andrew H. Wei contributed equally to this work Background: MBG453 is a high-affinity…
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Review
2018
Review
2018
Stromal biology and therapy in pancreatic cancer: ready for clinical translation?
A. Neesse
,
C. Bauer
,
+5 authors
T. Gress
Gut
2018
Corpus ID: 52149634
Pancreatic ductal adenocarcinoma (PDA) is notoriously aggressive and hard to treat. The tumour microenvironment (TME) in PDA is…
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2017
2017
Osteogenic and antibacterial properties of vancomycin-laden mesoporous bioglass/PLGA composite scaffolds for bone regeneration in infected bone defects
T. Cheng
,
Haiyun Qu
,
Guoyou Zhang
,
Xianlong Zhang
Artificial Cells Nanomedicine and Biotechnology
2017
Corpus ID: 30208686
Abstract Chronic osteomyelitis and infected bone defects are substantial challenges faced by orthopaedic surgeons. In this study…
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Review
2017
Review
2017
Function and mechanism of mesoporous bioactive glass adsorbed epidermal growth factor for accelerating bone tissue regeneration
Xiaoyan Wang
,
Wei Chen
,
+4 authors
Long Liu
Biomedical Materials
2017
Corpus ID: 46763351
Mesoporous bioactive glass (MBG) has been demonstrated to play a vital role in bone tissue engineering due to its bioactivity…
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2014
2014
Passive immunization against marinobufagenin attenuates renal fibrosis and improves renal function in experimental renal disease.
S. Haller
,
C. Drummond
,
+4 authors
J. Shapiro
American Journal of Hypertension
2014
Corpus ID: 35357628
BACKGROUND We have shown that the cardiotonic steroid marinobufagenin (MBG) is elevated in clinical and experimental renal…
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2008
2008
Marinobufagenin inhibits proliferation and migration of cytotrophoblast and CHO cells.
M. Uddin
,
D. Horvat
,
+5 authors
J. Puschett
Placenta
2008
Corpus ID: 37833302
2008
2008
In situ SAXRD study of sol-gel induced well-ordered mesoporous bioglasses for drug delivery.
Y. F. Zhao
,
S. Loo
,
Y. Z. Chen
,
F. Boey
,
J. Ma
Journal of Biomedical Materials Research. Part A
2008
Corpus ID: 27060885
In this work, two systems of mesoporous bioglasses (MBGs) were sol-gel derived using block copolymer pluronic F127 and P123…
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Highly Cited
2007
Highly Cited
2007
Mean blood glucose compared with HbA1c in the prediction of cardiovascular disease in patients with type 1 diabetes
E. Kilpatrick
,
A. Rigby
,
S. Atkin
Diabetologia
2007
Corpus ID: 23488091
Aims/hypothesisIt is not known whether mean blood glucose (MBG) predicts the risk of macrovascular complications in diabetes any…
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2007
2007
The potential of kales as a promising vegetable crop
M. Vilar
,
M. E. Cartea
,
G. Padilla
,
P. Soengas
,
P. Velasco
Euphytica
2007
Corpus ID: 8811200
Sixty varieties of kale (Brassica oleracea acephala group) from Galicia (northwestern Spain) were evaluated in two locations…
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Highly Cited
2001
Highly Cited
2001
The role of the Type I interferon response in the resistance of mice to filovirus infection.
M. Bray
Journal of General Virology
2001
Corpus ID: 35674319
Adult immunocompetent mice inoculated with Ebola (EBO) or Marburg (MBG) virus do not become ill. A suckling-mouse-passaged…
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