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Anti-TIM-3 Monoclonal Antibody MBG453

Known as: Anti-TIM3 Checkpoint Inhibitor MBG453, MBG 453, MBG453 
An inhibitor of the inhibitory T-cell receptor T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3; hepatitis A virus cellular… 
National Institutes of Health

Related topics

Related topics

1 relation
antigen binding

Papers overview

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2019
2019
Preparation and in vivo biocompatibility studies of different mesoporous bioactive glasses.
2019
2019
A Randomized, Double-Blind, Placebo-Controlled, Phase II Study of MBG453 Added to Hypomethylating Agents (HMAs) in Patients (pts) with Intermediate, High, or Very High Risk Myelodysplastic Syndrome…
Background and Rationale: Pts with higher-risk (HR; intermediate, high, or very high risk) MDS experience poor outcomes and have… 
2018
2018
Dual-Functional Dendritic Mesoporous Bioactive Glass Nanospheres for Calcium Influx-Mediated Specific Tumor Suppression and Controlled Drug Delivery in Vivo.
The development of nanomaterials for stable, controlled delivery of drugs and efficient suppression of tumor growth with… 
2017
2017
Osteogenic and antibacterial properties of vancomycin-laden mesoporous bioglass/PLGA composite scaffolds for bone regeneration in infected bone defects
Abstract Chronic osteomyelitis and infected bone defects are substantial challenges faced by orthopaedic surgeons. In this study… 
2017
2017
Overexpression of Tim-3 reduces Helicobacter pylori-associated inflammation through TLR4/NFκB signaling in vitro.
The present study aimed to investigate the interaction between T-cell immunoglobulin and mucin-domain-containing molecule-3 (Tim… 
2017
2017
Clotrimazole microemulsion and microemulsion‐based gel: evaluation of buccal drug delivery and irritancy using chick chorioallantoic membrane as the model
To investigate the efficacy of clotrimazole microemulsion (CTZ‐ME) and its gel form, clotrimazole microemulsion‐based gel (CTZ… 
2014
2014
Myocardial Tissue Perfusion Predicts the Evolution of Fragmented QRS in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
Background: Fragmented QRS complex (fQRS) is associated with worse outcomes in several cardiovascular conditions. However… 
2014
2014
How well do self-monitored capillary glucose measurements predict the mean blood glucose from 24-hour continuous monitoring in endocrine practice?
OBJECTIVE The mean blood glucose (MBG) level obtained from self-monitored capillary glucose (SMCG) data is a readily available… 
2008
2008
In situ SAXRD study of sol-gel induced well-ordered mesoporous bioglasses for drug delivery.
In this work, two systems of mesoporous bioglasses (MBGs) were sol-gel derived using block copolymer pluronic F127 and P123… 
2006
2006
[New method for detection of nonpalpable breast cancer].
OBJECTIVE The objective of the study was to evaluate the feasibility of radio guided occult lesion localization (ROLL) in the… 
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