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Anti-ErbB3 Monoclonal Antibody KTN3379

Known as: KTN3379 
A monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3) with potential antineoplastic activity. Anti-ErbB3… Expand
National Institutes of Health

Papers overview

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2019
2019
BYL719 is a PI3K inhibitor that has demonstrated efficacy in the treatment of head and neck squamous cell carcinoma. BYL719… Expand
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2017
2017
Head and neck squamous cell carcinoma (HNSCC) accounts for 3–5% of all tumor types and remains an unmet medical need with only… Expand
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2016
2016
Purpose: Human papillomavirus (HPV) 16 plays an etiologic role in a growing subset of head and neck squamous cell carcinomas… Expand
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2016
2016
HER3/ERBB3 is a kinase-deficient member of the EGFR family receptor tyrosine kinases (RTK) that is broadly expressed and… Expand
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2016
2016
2501Background: KTN3379 is a fully human anti-ErbB3 antibody with YTE half-life extension engineering that uniquely binds domain… Expand
2016
2016
We describe the management of subretinal fluid and macular oedema due to colorectal cancer metastasis to the choroid using… Expand
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2016
2016
ErbB3, the kinase-dead member of the EGFR/ErbB family, has been implicated as an oncogenic driver in a number of solid tumor… Expand
2016
2016
Background: Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with a rising incidence of more than 600,000… Expand
2015
2015
Significance Many cancers are driven by aberrant activation of members of the EGF receptor (EGFR) family including ErbB2 (HER2… Expand
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2015
2015
2598 Background: KTN3379 is a human monoclonal antibody against a unique epitope of human epidermal growth factor receptor-3… Expand