FAQ

Anti-CEA BiTE Monoclonal Antibody MEDI-565, Human

Known as: MEDI-565 
 

Topic mentions per year

Topic mentions per year

2010-2016
01220102016

Related topics

Related topics

1 relation
MT111

Related mentions per year

Related mentions per year

2010-2016
201020122014201620182020
Anti-CEA BiTE Monoclonal Antibody MEDI-565, Human
MT111

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Phase 1 Dose Escalation Study of MEDI-565, a Bispecific T-Cell Engager that Targets Human Carcinoembryonic Antigen, in Patients With Advanced Gastrointestinal Adenocarcinomas.
INTRODUCTION MEDI-565, a bispecific, single-chain antibody targeting human carcinoembryonic antigen on tumor cells and the CD3… (More)
Is this relevant?
2014
2014
CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas
Individual or combinations of somatic mutations found in genes from colorectal cancers can redirect the effects of chemotherapy… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2012
2012
The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA
MEDI-565 (also known as MT111) is a bispecific T-cell engager (BiTE®) antibody in development for the treatment of patients with… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2012
2012
In Vitro MABEL Approach for Nonclinical Safety Assessment of MEDI-565 (MT111)
85 Biotechnology-derived therapies (i.e., biologics such as antibodies) are products created by living organisms (bacterial… (More)
Is this relevant?
2010
2010
Metastatic colorectal cancer cells from patients previously treated with chemotherapy are sensitive to T-cell killing mediated by CEA/CD3-bispecific T-cell-engaging BiTE antibody
Background:Novel technologies to redirect T-cell killing against cancer cells are emerging. We hypothesised that metastatic human… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 3
  • figure 4
Is this relevant?