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Anti-CEA Antibody
Known as:
Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Antibody
, CEA Antibody
, Anti-CEACAM5 Antibody
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Any antibody against the tumor associated antigen carcinoembryonic antigen (CEA; CEACAM5), with potential antineoplastic activity. The CEA antigen is…
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National Institutes of Health
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Related topics
Related topics
2 relations
Immune System Processes
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
A label-free electrochemical immunoassay for carcinoembryonic antigen (CEA) based on gold nanoparticles (AuNPs) and nonconductive polymer film.
Hao Tang
,
Jinhua Chen
,
L. Nie
,
Y. Kuang
,
S. Yao
Biosensors & bioelectronics
2007
Corpus ID: 1207920
Highly Cited
2007
Highly Cited
2007
Predicting response to radioimmunotherapy from the tumor microenvironment of colorectal carcinomas.
Ethaar El Emir
,
U. Qureshi
,
+7 authors
R. Pedley
Cancer Research
2007
Corpus ID: 2690331
Solid tumors have a heterogeneous pathophysiology, which directly affects antibody-targeted therapies. Here, we consider the…
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Highly Cited
2006
Highly Cited
2006
A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol…
A. Mayer
,
R. Francis
,
+11 authors
R. Begent
Clinical Cancer Research
2006
Corpus ID: 6099095
Purpose: Antibody-directed enzyme prodrug therapy is a two-stage treatment whereby a tumor-targeted antibody-enzyme complex…
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Highly Cited
2003
Highly Cited
2003
Optimizing bispecific antibody pretargeting for use in radioimmunotherapy.
R. Sharkey
,
H. Karacay
,
+7 authors
D. Goldenberg
Clinical Cancer Research
2003
Corpus ID: 9328252
PURPOSE With increasing interest in pretargeting procedures for improving the delivery of radionuclides for cancer imaging and…
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2002
2002
Tumour targeting of humanised cross-linked divalent-fab′ antibody fragments: a clinical phase I/II study
J. L. Casey
,
M. Napier
,
+8 authors
R. Begent
British Journal of Cancer
2002
Corpus ID: 10795331
Antibody engineering has made it possible to design antibodies with optimal characteristics for delivery of radionuclides for…
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Highly Cited
2001
Highly Cited
2001
An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA.
M. R. Lewis
,
J. Kao
,
A. Anderson
,
J. Shively
,
A. Raubitschek
Bioconjugate chemistry
2001
Corpus ID: 30926204
A simple, water-soluble procedure for conjugation of monoclonal antibodies to 1,4,7,10-tetraazacyclododecane-N,N',N",N…
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Highly Cited
2001
Highly Cited
2001
Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications.
P. Yazaki
,
L. Shively
,
+6 authors
A. Wu
JIM - Journal of Immunological Methods
2001
Corpus ID: 24053449
Highly Cited
1999
Highly Cited
1999
Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent.
R. Pedley
,
S. Sharma
,
+5 authors
R. Begent
Cancer Research
1999
Corpus ID: 16367727
The irregular nature of solid tumor vasculature produces a heterogeneous distribution of antibody-targeted therapies within the…
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Highly Cited
1998
Highly Cited
1998
Expression in cytotoxic T lymphocytes of a single‐chain anti‐carcinoembryonic antigen antibody. Redirected Fas ligand‐mediated lysis of colon carcinoma
P. Darcy
,
M. Kershaw
,
J. Trapani
,
M. Smyth
European Journal of Immunology
1998
Corpus ID: 21655543
In the MD45 mouse cytotoxic T lymphocyte (CTL) hybridoma cell line, we have expressed a chimeric receptor, consisting of the…
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Highly Cited
1996
Highly Cited
1996
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts.
S. Hu
,
L. Shively
,
+5 authors
A. Wu
Cancer Research
1996
Corpus ID: 14363948
A novel engineered antibody fragment (VL-VH-CH3, or "minibody") with bivalent binding to carcinoembryonic antigen (CEA) was…
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