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Anti-CEA Antibody

Known as: Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Antibody, CEA Antibody, Anti-CEACAM5 Antibody 
Any antibody against the tumor associated antigen carcinoembryonic antigen (CEA; CEACAM5), with potential antineoplastic activity. The CEA antigen is… 
National Institutes of Health

Related topics

Related topics

2 relations
Immune System Processesantigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
A label-free electrochemical immunoassay for carcinoembryonic antigen (CEA) based on gold nanoparticles (AuNPs) and nonconductive polymer film.
Highly Cited
2007
Highly Cited
2007
Predicting response to radioimmunotherapy from the tumor microenvironment of colorectal carcinomas.
Solid tumors have a heterogeneous pathophysiology, which directly affects antibody-targeted therapies. Here, we consider the… 
Highly Cited
2006
Highly Cited
2006
A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol…
Purpose: Antibody-directed enzyme prodrug therapy is a two-stage treatment whereby a tumor-targeted antibody-enzyme complex… 
Highly Cited
2003
Highly Cited
2003
Optimizing bispecific antibody pretargeting for use in radioimmunotherapy.
PURPOSE With increasing interest in pretargeting procedures for improving the delivery of radionuclides for cancer imaging and… 
2002
2002
Tumour targeting of humanised cross-linked divalent-fab′ antibody fragments: a clinical phase I/II study
Antibody engineering has made it possible to design antibodies with optimal characteristics for delivery of radionuclides for… 
Highly Cited
2001
Highly Cited
2001
An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA.
A simple, water-soluble procedure for conjugation of monoclonal antibodies to 1,4,7,10-tetraazacyclododecane-N,N',N",N… 
Highly Cited
2001
Highly Cited
2001
Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications.
Highly Cited
1999
Highly Cited
1999
Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent.
The irregular nature of solid tumor vasculature produces a heterogeneous distribution of antibody-targeted therapies within the… 
Highly Cited
1998
Highly Cited
1998
Expression in cytotoxic T lymphocytes of a single‐chain anti‐carcinoembryonic antigen antibody. Redirected Fas ligand‐mediated lysis of colon carcinoma
In the MD45 mouse cytotoxic T lymphocyte (CTL) hybridoma cell line, we have expressed a chimeric receptor, consisting of the… 
Highly Cited
1996
Highly Cited
1996
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts.
A novel engineered antibody fragment (VL-VH-CH3, or "minibody") with bivalent binding to carcinoembryonic antigen (CEA) was… 
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